Results 151 to 160 of about 91,948 (306)
Advanced Science, EarlyView.ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao +12 more
wiley +1 more source
Understanding the Implications of Choice of Deprivation Index for Measuring Consistent Poverty in Ireland. ESRI WP181. February 2007 [PDF]
, 2007 In this paper we make use of the Irish component of the European Union Community Statistics on Income and Living Conditions (EU-SILC) survey for 2004 in order to develop a measure of consistent poverty that overcomes some of the difficulties associated ...
Whelan, Christopher T.
core
Advanced Science, EarlyView.Various spillover‐mediated electrocatalytic reactions, such as hydrogen and oxygen evolution, carbon dioxide and nitrogen reduction, and methanol oxidization reactions, are systematically summarized. Abstract Spillover phenomenon, which is characterized by the dynamic migration of active species across catalyst surfaces, provides a promising avenue to ...
Di Wang +5 more
wiley +1 more source
Are social exclusion and poverty measures interrelated? A study with Spanish data [PDF]
, 2012 One of the targets of Europe's growth strategy (Europe 2020) is "reduction of poverty by aiming to lift at least 20 million people out of the risk of poverty or social exclusion".
Calvo, José L. +2 more
core
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
Advanced Science, EarlyView.T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Monoaminylation in Human Health and Disease: State of the Field, Challenges, and Emerging Directions
Advanced Science, EarlyView.This review delineates monoaminylation—serotonylation, dopaminylation, and histaminylation—as key post‐translational modifications beyond receptor signaling. It details their catalytic mechanisms, roles in gene expression and protein function, and implications in health and disease, aiming to bridge mechanistic insights with therapeutic potential ...
Yiqi Zhao +4 more
wiley +1 more source
Integrating Spatial Proteogenomics in Cancer Research
Advanced Science, EarlyView.Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
Nepal Multidimensional Poverty Index: Analysis towards action
, 2021 This report provides the first update to Nepal’s official national Multidimensional Poverty Index (MPI). While the first MPI used 2014 data from the Nepal Multiple Indicator Cluster Survey (NMICS), the updated MPI in this report uses 2019 data from the same NMICS report.
openaire +1 more source
Advancing Precision Nutrition Through Multimodal Data and Artificial Intelligence
Advanced Science, EarlyView.Individual responses to food vary dramatically, challenging traditional dietary advice. This review explores how the unique genetic makeup, gut microbiome, and brain activity shape host metabolic health. We examine how artificial intelligence integrates these multimodal data to predict individualized dietary needs, moving beyond one‐size‐fits‐all ...
Yuanqing Fu +5 more
wiley +1 more source
Global Multidimensional Poverty Index 2014 [PDF]
, 2014 Sabina Alkire +4 more
openaire +2 more sources