Results 251 to 260 of about 6,499,111 (308)
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
High‐Conductivity Electrolytes Screened Using Fragment‐ and Composition‐Aware Deep Learning
We present a new deep learning framework that hierarchically links molecular and functional unit attributions to predict electrolyte conductivity. By integrating molecular composition, ratios, and physicochemical descriptors, it achieves accurate, interpretable predictions and large‐scale virtual screening, offering chemically meaningful insights for ...
Xiangwen Wang +6 more
wiley +1 more source
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Arce, Constantino, Gärling, Tomy
openaire +2 more sources
Lithium‐ion battery degradation arises from complex, localized processes during operation, limiting long‐term performance. In situ electrochemical liquid cell TEM provides unique access to these mechanisms. This review summarizes degradation phenomena revealed by liquid cell TEM, traces the evolution of the three main cell designs, compares their ...
Walid Dachraoui, Rolf Erni
wiley +1 more source
A series of through‐space coupled donor‐acceptor (D–A) molecules is sandwiched between two electrodes to determine their single‐molecule conductance. As the D–A interaction weakens, single‐molecule conductance reduces while Flicker Noise PSD n‐value increases (coupling strength decreases).
Xin Wang +10 more
wiley +1 more source
Fluorinated N‐oxide aza‐BODIPY nanoemulsions integrate fluorination‐driven molecular design with co‐assembly in fluorinated oil for multimodal imaging‐guided phototherapy. The co‐assembly redshifts fluorescence into the NIR‐II window for deep‐tissue imaging and provides a unified 19F signal for background‐free, quantitative MRI.
Anfeng Li +5 more
wiley +1 more source
Using multidimensional scaling to organize expected outcomes of engineering education
Roger Hadgraft +2 more
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