ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou +9 more
wiley +1 more source
Symptom management in cancer care: An evolutionary concept analysis for a digitally enabled collaborative framework. [PDF]
Yu W +5 more
europepmc +1 more source
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source
Physical literacy in older adults: An evolutionary concept analysis. [PDF]
Yang J +5 more
europepmc +1 more source
A one‐pot, aqueous, and scalable method for synthesizing chiral lanthanide supramolecular emitters using terbium and threonine is reported. The aqueous solution of these chiral emitters displays the following features: (i) 100 % transparency, (ii) tunable luminescence and CPL, and (iii) a pH feedback loop that controls the “on‐off” states of ...
P. M. Ajay Sekhar +5 more
wiley +1 more source
Outcome-framework adherence in neuromodulation studies for chronic pain: evidence from a systematic gap map. [PDF]
Goudman L +4 more
europepmc +1 more source
From Sensing Mechanisms to System Co‐Design: Graphene‐Based Sensors and Readout Circuits
This review establishes a unified PS–EQ–RF framework linking graphene sensing mechanisms, native electrical outputs, and output‐specific readout circuits. Voltage‐, current‐, resistance‐, and capacitance‐type sensing systems are systematically classified to guide architecture selection, low‐noise design, system co‐design, and practical integration ...
Jinduo Zhang +5 more
wiley +1 more source
Commentary on: "Mapping the commonalities of rehabilitation: using GUIDE-rehab to open the black box of programmes across diverse health conditions". [PDF]
Boldrini P, Zampolini M.
europepmc +1 more source
Twin‐Lever Multifunctional Meta‐Optics With High Longitudinal Tolerance
We introduce a single‐layer, CMOS‐compatible metasurface that allows for polarization‐programmable, achromatic broadband dual‐mode imaging with high longitudinal tolerance. The twin‐lever design combines bright‐field focusing and vortex‐based edge‐enhanced imaging while managing axial intensity distribution from 488 to 633 nm.
Isma Javed +10 more
wiley +1 more source
Pre-loss grief among family caregivers: An evolutionary concept analysis. [PDF]
Qian Y +5 more
europepmc +1 more source

