Results 71 to 80 of about 3,625,402 (300)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Day patient treatment for traumatic grief: preliminary evaluation of a one-year treatment programme for patients with multiple and traumatic losses

European Journal of Psychotraumatology, 2017
Background: Bereaved individuals who have lost a loved one under traumatic circumstances can develop symptoms of Persistent Complex Bereavement Disorder (PCBD) and/or Posttraumatic Stress Disorder (PTSD).
Annemiek de Heus, Sophie M. C. Hengst, Simone M. de la Rie, A. A. A. Manik J. Djelantik, Paul A. Boelen, Geert E. Smid   +5 more
doaj   +1 more source

Characteristics of women seeking care at a vulvar clinic: A study of 600 patients during a 17‐year period

JEADV Clinical Practice, 2023
Background Symptoms from the vulva and vagina affect about one‐third of all women and have a negative influence both on sexual health and psychosocial well‐being. Research regarding vulvar diseases is sparse and there is a need for a better understanding
Karolina Rosendahl, Alexander Shayesteh, Elisabet Nylander   +2 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

BIBLIOMETRIC ANALYSIS OF THE ANPROTEC CONFERENCE ANNALS

Revista Produção e Desenvolvimento, 2019
The paper aims to analyze the characteristics of the publications of the annals of the conferences of the National Association of Entities Promoting Innovative Enterprises (Anprotec).
Leani Lauermann Koch, Claudio Alcides Jacoski, Odilon Luiz Poli, Bruna Furlanetto, Giana de Vargas Mores   +4 more
doaj   +1 more source

Biosimilars: A Multidisciplinary Perspective [PDF]

Clinical Therapeutics, 2016
A biosimilar is an officially regulated and approved copy of an originator biologic therapy. Improved affordability and consequent wider patient access compared with biologics are a significant appeal of biosimilars. Regulatory guidelines for biosimilar development and approval are rigorous and undergoing constant refinement.
Khraishi, Majed, Stead, David, Lukas, Milan, Scotte, Florian, Schmid, Holger   +4 more
openaire   +2 more sources

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Cloenda

Digithum, 2004
En aquest breu document, el director de la titulació d'Humanitats de la UOC, Miquel Strubell, clou el dossier monogràfic que dimana de la I Jornada sobre les Professions de les Humanitats en la Societat del Coneixement tot destacant aquells eixos de ...
Miquel Strubell
doaj   +1 more source

Multidisciplinary care of craniosynostosis

Journal of Multidisciplinary Healthcare, 2017
The management of craniosynostosis, especially in the setting of craniofacial syndromes, is ideally done in a multidisciplinary clinic with a team focused toward comprehensive care. Craniosynostosis is a congenital disorder of the cranium, caused by the premature fusion of one or more cranial sutures.
Edward Buchanan, Yunfeng Xue, Amy Xue, Asaf Olshinka, Sandi Lam   +4 more
openaire   +5 more sources