Results 151 to 160 of about 2,523,054 (252)

Multidisciplinary Therapeutic Approaches to Pancreatic Cancer According to the Resectability Status

open access: yes
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers, characterized by late diagnosis, rapid progression, and limited therapeutic options.
Marco Bardone   +14 more
core   +1 more source

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu   +7 more
wiley   +1 more source

Optimising Patient Outcomes in Tongue Cancer: A Multidisciplinary Approach

open access: yes
A multidisciplinary approach to the management of tongue cancer is vital for achieving optimal patient outcomes. Nursing and allied health professionals play essential roles within the team.
David Rowe   +30 more
core   +1 more source

Yoda1‐Functionalized Nanozymes Coordinate Piezo1 Activation and Mitochondrial Protection to Reprogram the Diabetic Osteoimmune Micromilieu and Promote Vascularized Bone Repair

open access: yesAdvanced Science, EarlyView.
Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng   +16 more
wiley   +1 more source

Ultrafast Micrometric Laser Structuring of Polymer Surfaces for Highly Organized Skeletal Muscle Tissue Modeling

open access: yesAdvanced Science, EarlyView.
Standard cell culture supports were functionalized by laser‐structuring to generate advanced topographies tailored to skeletal muscle tissue. The physicochemical modifications of the polymeric surfaces and their interactions with cells were thoroughly investigated, confirming both safety and effectiveness in guiding muscle cell organization.
Lucas Duvert   +10 more
wiley   +1 more source

Assessing the Impact of Multidisciplinary Collaboration on Quality of Life in Older Patients Receiving Primary Care: Cross Sectional Study

open access: yes
The growing aging population presents unique challenges in maintaining their quality of life (QoL), which encompasses physical, psychological, and social wellbeing.
Mohammed Nasser Albarqi   +1 more
core   +1 more source

Interface Rectification via Roll‐to‐Roll Dual‐Confinement Nanocoatings for High‐Temperature Polymer Capacitors

open access: yesAdvanced Science, EarlyView.
Dual confinement in self‐assembled nanocoatings regulates polymer dynamics and hot‐carrier transport, enabling an interface‐rectification strategy for high‐temperature polymer capacitive energy storage. ABSTRACT Polymer film capacitors are indispensable for energy storage and power conversion, yet their energy density and efficiency deteriorate rapidly
Ning Guo   +14 more
wiley   +1 more source

Water‐Coupled Interfacial Modulation Enhances Photovoltaic and Pyroelectric Responses in Transparent Self‐Powered ZnO/NiO Photodetectors

open access: yesAdvanced Science, EarlyView.
Direct water contact enhances the performance of a transparent self‐powered FTO/ZnO/NiO/AgNW/ZnO UV photodetector. Reduced surface reflection improves optical transmission, while an electric double layer at the ZnO/water interface modulates interfacial electrostatics and promotes charge separation.
Seunghee Cho   +6 more
wiley   +1 more source

In Vivo CRISPR Screen Identifies RPS19 as an Immunotherapy Target in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
By employing in vivo CRISPR functional screening, we identify ribosomal protein RPS19 as a pivotal mediator driving immune evasion in hepatocellular carcinoma, wherein tumor‑released RPS19 binds C5aR1 on tumor‑associated macrophages to initiate downstream immunosuppressive signaling; SP94‑peptide‑modified SNPSS nanoparticles deliver Cas9/sgRPS19 ...
Lei He   +20 more
wiley   +1 more source

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