This study reports D34 as the first PROTAC degrader that targets the 3C protease of picornaviruses. D34 effectively degrades EV71 3C protease via the ubiquitin‐proteasome pathway. More importantly, D34 exhibits a high resistance barrier and shows broad‐spectrum antiviral activity against multiple picornaviruses, highlighting its potential as a novel ...
Weilong Deng +9 more
wiley +1 more source
Multidisciplinary Management of Emergency Neurosurgery for Intracerebral Hemorrhage During Pregnancy: A Case Report. [PDF]
Case E +8 more
europepmc +1 more source
Terahertz Channel Modeling, Estimation and Localization in RIS‐Assisted Systems
Reconfigurable intelligent surfaces have become a recent intensive research focus. Based on practical applications, channel strategies for RIS‐assisted terahertz wireless communication systems are categorized into three different types: channel modeling, channel estimation, and channel localization.
Hongjing Wang +9 more
wiley +1 more source
Relapsing Nasal Septal Leishmaniasis: Lessons in Long-Term Multidisciplinary Management Case Report. [PDF]
Ehsan E +3 more
europepmc +1 more source
Advancing Energy Materials by In Situ Atomic Scale Methods
Progress in in situ atomic scale methods leads to an improved understanding of new and advanced energy materials, where a local understanding of complex, inhomogeneous systems or interfaces down to the atomic scale and quantum level is required. Topics from photovoltaics, dissipation losses, phase transitions, and chemical energy conversion are ...
Christian Jooss +21 more
wiley +1 more source
Severe Sepsis After Vaginal Delivery: A Case Report. [PDF]
Dehghan M.
europepmc +1 more source
From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku +5 more
wiley +1 more source
Healthcare professionals' knowledge and views on unmet needs in prevention of infectious comorbidities in pregnant women with inflammatory rheumatic diseases. [PDF]
Yerlanova D +5 more
europepmc +1 more source
Multidisciplinary team working
Taylor, Cath, Green, James
openaire +4 more sources
Smart Exploration of Perovskite Photovoltaics: From AI Driven Discovery to Autonomous Laboratories
In this review, we summarize the fundamentals of AI in automated materials science, and review AI applications in perovskite solar cells. Then, we sum up recent progress in AI‐guided manufacturing optimization, and highlight AI‐driven high‐throughput and autonomous laboratories.
Wenning Chen +4 more
wiley +1 more source

