Results 91 to 100 of about 12,729,014 (274)

Multidisciplinary Design Optimization of a Novel Sandwich Beam-Based Adaptive Tuned Vibration Absorber Featuring Magnetorheological Elastomer. [PDF]

Materials (Basel), 2020
Asadi Khanouki M, Sedaghati R, Hemmatian M.   +2 more
europepmc   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Translational Barriers and AI‐Driven Challenges of Microfluidics‐Enabled Wearables and Implantable Systems in Personalized Medicine

Advanced Science, EarlyView.
An integrative review of microfluidics‐enabled wearables and implantable systems reveals a single‐track translation pipeline, bridging functional biomaterials with clinical utility. Dynamic feedback loops driven by artificial intelligence advance diagnostics toward personalized closed‐loop theranostics.
Ke Huang, Ching Yin Fong, Xin Huang, Bee Luan Khoo   +3 more
wiley   +1 more source

OPTIMIZATION DESIGN OF SEALED-MODULE STRUCTURE BASED ON ISIGHT PLATFORM

Jixie qiangdu, 2016
Based on i SIGHT multidisciplinary optimization platform integrated finite element analysis software ABAQUS,the sub-model technology,global optimization strategy,hybrid iterative optimization algorithm and parametric modeling method of spline curve were ...
SUN Wei, NIU Fei, WANG XiaoYu, ZENG FuMing   +3 more
doaj  

Comparison Between Traditional Method (Statistical Method) and Multidisciplinary Optimization Method (AAO) in Designing of a Lightweight Liquid Propellant LV [PDF]

فصلنامه علوم و فناوری فضایی, 2012
One of the most important problems that nowadays are common in aerospace societies in Iran and also around the world is how to optimize the designing of the flight objects.
S. M. Hashemi Doulabi, H. Darabi, J. Roshnian   +2 more
doaj  

Orthogonal-Array based Design Methodology for Complex, Coupled Space Systems [PDF]

, 2010
The process of designing a complex system, formed by many elements and sub-elements interacting between each other, is usually completed at a system level and in the preliminary phases in two major steps: design-space exploration and optimization.
Mooij, Erwin, Corpino, Sabrina, Stesina, Fabrizio, Cardile, Diego, Ridolfi, Guido   +4 more
core  

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

Advanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki, Yoshitaka Koseki, Kunikazu Ishii, Minsang Kim, Keita Tanita, Kota Sato, Toru Nakazawa, Satoshi Katsube, Daisuke Unabara, Tasuku Hamaguchi, Keisuke Kawakami, Koji Yonekura, Akihide Hibara, Atsushi Wakamiya, Hiroshi Uji‐I, Hitoshi Kasai   +18 more
wiley   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

Advanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee, Jihyang Park, Xinyi Wang, Yueqi Deng, Jiashu Ren, Tao Zhou   +5 more
wiley   +1 more source

Small Launchers Design and Cost Balance Improvements

Engineering Proceedings
The improvement of the design of space launchers, with a consequent reduction in development costs, has not been achieved to the same extent as in the case of satellite designs, even when applying similar Concurrent Engineering processes and MBSE ...
Rubén González-González, Andrés García-Pérez, Gustavo Alonso Rodrigo   +2 more
doaj   +1 more source