Results 31 to 40 of about 12,552,112 (178)

Multi-Fidelity Gradient-Based Optimization for High-Dimensional Aeroelastic Configurations

Algorithms, 2022
The simultaneous optimization of aircraft shape and internal structural size for transonic flight is excessively costly. The analysis of the governing physics is expensive, in particular for highly flexible aircraft, and the search for optima using ...
Andrew S. Thelen, Dean E. Bryson, Bret K. Stanford, Philip S. Beran   +3 more
doaj   +1 more source

Multidisciplinary design optimization framework for the pre design stage [PDF]

, 2010
Presented is a novel framework for performing flexible computational design studies at preliminary design stage. It incorporates a workflow management device (WMD) and a number of advanced numerical treatments, including multi-objective optimization ...
Balachandran, Libish Kalathil, Padulo, Mattia, Paolo Fantini, Nunez, Marco, Marin Guenov, Libish Balachandran, Guenov, Marin D., Maginot, Jeremy, Marco Nunez, Mattia Padulo, Jeremy Maginot, Fantini, Paolo   +11 more
core   +1 more source

Optimization Approaches for Battery Pack Layout and Integration: A Review of Methods, Tools, and Research Gaps [PDF]

MATEC Web of Conferences
Electric vehicle (EV) battery packs strongly influence vehicle performance, safety, cost, and energy efficiency. This paper presents a structured review of optimization approaches for EV battery-pack design, focusing on four interacting domains ...
Sharifi Mohammad Shariati, Persson Johan
doaj   +1 more source

Invasive Assessment of Right Ventricular Dysfunction Predicts Periprocedural Outcomes in Patients Undergoing Unplanned Ventricular Tachycardia Ablation

Journal of Cardiovascular Electrophysiology, Volume 37, Issue 8, Page 1699-1708, August 2026.
Displays bar graphs showing outcome rates stratified by clinical and hemodynamic variables. Asterisks (*) denote statistically significant differences (p ≤ 0.05). “NS” indicates non‐significant comparisons. Percentages are shown above each bar. The top panel corresponds to acute kidney injury (blue bars), and the bottom panel corresponds to acute ...
Tess Calcagno, Sai Prasad Ramachandran, V. Karthik, Mendpara Vaidehi, Andrew Cesmat, Joseph Sipko, Bryan Baranowski, Mandeep Bhargava, Thomas D. Callahan, Mina K. Chung, Thomas Dresing, Ayman A. Hussein, Mohamed Kanj, Arshneel Kochar, David O. Martin, Walid I. Saliba, Tyler L. Taigen, Niraj Varma, Koji Higuchi, Justin Z. Lee, Oussama M. Wazni, Andres Carmona Rubio, Pasquale Santangeli, Jakub Sroubek   +23 more
wiley   +1 more source

Multipoint Aerostructural Optimization of Wind Turbine Rotors Using a Coupled Blade‐Resolved Aerostructural Solver

Wind Energy, Volume 29, Issue 7, July 2026.
ABSTRACT Physics‐based design optimization workflows thread the needle between computational cost limitations and simulation complexity, often compromising between modeling detail and the range of operating design conditions. Multipoint aerostructural optimization of wind turbine rotors has so far been confined to low‐fidelity analyses or to high ...
Marco Mangano, Eirikur Jonsson, Yingqian Liao, Denis‐Gabriel Caprace, Andrew Ning, Joaquim R. R. A. Martins   +5 more
wiley   +1 more source

Multidisciplinary Design Optimization and Analysis of Hydrazine Monopropellant Propulsion System

International Journal of Aerospace Engineering, 2015
Monopropellant propulsion systems are widely used especially for low cost attitude control or orbit correction (orbit maintenance). To optimize the total propulsion system, subsystems should be optimized.
Amirhossein Adami, Mahdi Mortazavi, Mehran Nosratollahi, Mohammadreza Taheri, Jalal Sajadi   +4 more
doaj   +1 more source

Structure‐ and Ligand‐Based Discovery of Novel 3‐Chymotrypsin‐Like Protease Nonpeptidomimetic Hits

ChemMedChem, Volume 21, Issue 7, 14 April 2026.
A multistep virtual screening cascade, integrating shape‐based, ensemble docking, and quantitative structure–activity relationship (QSAR) models, was employed to screen 1.5 million compounds. This funnel identified a novel 3‐chymotrypsin‐like protease (3CLpro) inhibitor, LabMol‐499, which was experimentally validated using a Förster Resonance Energy ...
Sabrina Silva‐Mendonça, Donald Seanego, Christopher Jurisch, Melina Mottin, Flávia Nader Motta, Beatriz S. A. Rodrigues, Gilberto S. M. Junior, Alexandra Maria dos Santos Carvalho, Fábio Muniz de Oliveira, Sunniva Sigurdardóttir, Per Sunnerhagen, Izabela Marques Dourado Bastos, Richard Gessner, Kelly Chibale, Carolina Horta Andrade   +14 more
wiley   +1 more source

A Universal MDO Framework Based on the Adaptive Discipline Surrogate Model

International Journal of Aerospace Engineering, 2018
High time-consuming computation has become an obvious characteristic of the modern multidisciplinary design optimization (MDO) solving procedure. To reduce the computing cost and improve solving environment of the traditional MDO solution method, this ...
Hua Su, Chun-lin Gong, Liang-xian Gu
doaj   +1 more source

From Natural Language to Executable Optimization Workflows: A Knowledge-Graph-Driven Framework for Multidisciplinary Optimization [PDF]

MATEC Web of Conferences
Early-stage engineering design requires balancing competing performance, cost, and feasibility criteria across interacting disciplinary models. However, deploying multidisciplinary optimization (MDO) frameworks remains difficult because translating high ...
Hakkak Aref Aghaee, Wiberg Anton, Tarkian Mehdi   +2 more
doaj   +1 more source

Identification of Missing Knowledge in MBSE System Models Using Graph‐Based Machine Learning

Systems Engineering, Volume 29, Issue 2, Page 133-149, March 2026.
ABSTRACT The design and development of complex aerospace systems pose significant challenges due to their growing complexity. Iterative design processes, guided by formal specifications, strive to refine initially vague characteristics through multiple stages.
Esma Karagoz, Olivia J. Pinon Fischer, Dimitri Mavris   +2 more
wiley   +1 more source