Results 111 to 120 of about 648,569 (296)

Synchronous metastases from colorectal cancer. Treatment and long-term survival compared to patients with metachronous metastases: a population-based study from Central Norway 2001–2015

open access: yesActa Oncologica
Background: Reliable and modern information on primary evaluation, treatment, and long-term survival rates for patients with colorectal cancer (CRC) metastases are needed.
Per Even Storli   +6 more
doaj   +1 more source

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

open access: yesAdvanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue   +17 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

open access: yesAdvanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang   +7 more
wiley   +1 more source

MicrobeDiscover: A Knowledge Graph–Enabled AI Framework for Identifying Microbes for Inorganic Nanomaterial Biosynthesis

open access: yesAdvanced Science, EarlyView.
Microbial synthesis of nanomaterials (NMs) is eco‐friendly, but the screening of microorganisms is limited by inefficient traditional methods (currently only involving∽400 microorganisms/90 NMs). We propose AI framework MicrobeDiscover, integrating a knowledge graph of microbe‐NM interactions.
Ludi Wang   +12 more
wiley   +1 more source

Mind the Gap: Addressing Unconscious Bias in Multidisciplinary Team Ideation

open access: yesCERN IdeaSquare Journal of Experimental Innovation
While corporate innovation serves as a pivotal competitive advantage for firms, the subtle influence of cognitive biases on the creative process cannot be underestimated. This study aims to explore the extent to which unconscious bias limits ideation
Kamilla Dajani, Jozef Šaranko
doaj   +1 more source

The effect of multidisciplinary team care on cancer management

open access: yesThe Pan African Medical Journal, 2011
Over the past 15 years, the multidisciplinary team management of many medical conditions especially cancers has increasingly taken a prominent role in patient management in many hospitals and medical centres in the developed countries.
Ganiy Opeyemi Abdulrahman Jnr
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Factors influencing interprofessional collaboration in general and during multidisciplinary team meetings in long-term care and geriatric rehabilitation: a qualitative study

open access: yesBMC Medical Education
Background Interprofessional collaboration is essential to maintain high-quality care in long-term care and geriatric rehabilitation. However, little is known regarding perceived factors influencing interprofessional collaboration by people involved in ...
Arno J. Doornebosch   +2 more
doaj   +1 more source

ENMat international projects: FP7 NMP coordination action: 2BFUNTEX [PDF]

open access: yes, 2012
Boosting collaboration between research centres and industry to enhance rapid industrial uptake of innovative functional textile structures and textile-related materials in a mondial market 2BFUNTEX will exploit the untapped potential in functional ...
Kiekens, Paul, Van der Burght, Els
core   +1 more source

Copper Contact for Perovskite Solar Cells: Properties, Interfaces, and Scalable Integration

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Copper electrodes, as low‐cost, scalable contacts for perovskite solar cells, offer several advantages over precious metals such as Au and Ag, including performance, cost, deposition methods, and interfacial engineering. Copper (Cu) electrodes are increasingly considered practical, sustainable alternatives to noble‐metal contacts in perovskite solar ...
Shuwei Cao   +4 more
wiley   +1 more source

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