Results 141 to 150 of about 9,659,841 (296)

Multidisciplinary Treatment for Glioblastoma

Japanese Journal of Neurosurgery, 2022
Takashi Sasayama, Kazuhiro Tanaka, Hiroaki Nagashima   +2 more
openaire   +2 more sources

Metabolic Reprogramming in Glioblastoma Stem Cells Promotes Radiation Resistance Through a H3K18la/USP30/MBOAT2 Axis

Advanced Science, EarlyView.
LDHA‐driven lactate production in mesenchymal glioma stem cells promotes p300‐dependent H3K18 lactylation, activates USP30 transcription, and stabilizes MBOAT2 to remodel phosphatidylethanolamines toward ferroptosis‐resistant PE‐MUFA species. Disrupting this metabolic–epigenetic–lipid circuit enhances ferroptosis and sensitizes glioblastoma to ...
Zong Miao, Wei Gu, Yimin Ren, Chenfei Lu, Wanzhi Cai, Junnan Lu, Zhongyuan Bao, Yanan Zhou, Rong Li, Ke Jin, Chao Chen, Hongxiang Wang, Lei Xu, Juxiang Chen   +13 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Multidisciplinary Treatment for Esophagogastric Junction Cancer From a Dutch Perspective. [PDF]

Ann Gastroenterol Surg
Overtoom HCG, Gisbertz SS.
europepmc   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Fratura coronorradicular: uma abordagem multidisciplinar

Revista de Odontologia da UNESP
INTRODUÇÃO: Uma fratura coronorradicular envolve esmalte, dentina e cemento, podendo ou não haver comprometimento pulpar. Vários tratamentos são propostos na literatura, desde a colagem do fragmento dental até a extrusão cirúrgica do fragmento ...
Maíra do Prado, Brenda Paula Figueiredo de Almeida Gomes, Elise Lanziotti Telles, Marcos Cesar Pimenta de Araújo, Heloísa Carla Gusman   +4 more
doaj  

Quantitative Visualization of Intracellular Nanometabolism Using Peak‐Shifted Dual‐State Emissive FRET Nanoprobes

Advanced Science, EarlyView.
This study reveals the long‐elusive intracellular dissolution mechanism of carrier‐free nanomedicines. By utilizing peak‐shifted dual‐state emissive FRET nanoprobes (PDFNPs) that undergo a distinct ratiometric fluorescence peak shift upon disassembly, we achieve real‐time, quantitative tracking of dissolution kinetics in live cells.
Farsai Taemaitree, Jinwoo Sung, Yutaro Miki, Ryuju Suzuki, Yoshitaka Koseki, Kunikazu Ishii, Minsang Kim, Keita Tanita, Kota Sato, Toru Nakazawa, Satoshi Katsube, Daisuke Unabara, Tasuku Hamaguchi, Keisuke Kawakami, Koji Yonekura, Akihide Hibara, Atsushi Wakamiya, Hiroshi Uji‐I, Hitoshi Kasai   +18 more
wiley   +1 more source

520 Initial strategy of corticosteroids-immunosuppressant treatment and the consequent clinical outcome among non-small cell lung cancer patients with severe checkpoint inhibitor pneumonitis

Journal for ImmunoTherapy of Cancer, 2023
Ting Mei, Youling Gong
doaj   +1 more source

Refining the role of extended resection in multidisciplinary treatment for cT4b esophageal cancer. [PDF]

J Thorac Dis
Makino T, Yamasaki M, Miyagawa S, Eguchi H, Doki Y.   +4 more
europepmc   +1 more source

Microplastics in Wastewater Treatment Plants: Characteristics, Occurrence and Removal Technologies

Pollution of the aquatic environment with microplastics has recently been recognised as a new environmental threat considering their negative impact on the ecosystem.
Czesława Rosik-Dulewska, Alina Pohl, Michał Bodzek   +2 more
core   +1 more source