Results 101 to 110 of about 1,300,615 (222)

Microfluidic Multielectrode Arrays for Spatially Localized Drug Delivery and Electrical Recordings of Primary Neuronal Cultures

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Neuropathological models and neurological disease progression and treatments have always been of great interest in biomedical research because of their impact on society.
Giulia Bruno   +9 more
doaj   +1 more source

Using a virtual cortical module implementing a neural field model to modulate brain rhythms in Parkinson's disease

open access: yesFrontiers in Neuroscience, 2010
We propose a new method for selective modulation of cortical rhythms based on neural field theory, in which the activity of a cortical area is extensively monitored using a two-dimensional microelectrode array.
Julien Modolo   +5 more
doaj   +1 more source

Obtaining Multi-electrode Array Recordings from Human Induced Pluripotent Stem Cell–Derived Neurons

open access: yesBio-Protocol, 2017
Neuronal electrical properties are often aberrant in neurological disorders. Human induced pluripotent stem cells (hiPSCs)-derived neurons represent a useful platform for neurological disease modeling, drug discovery and toxicity screening in vitro ...
Xiaohong Xu   +3 more
doaj   +1 more source

Improving Kv7 targeting anticonvulsants ‐ will repurposing save the day?

open access: yes
British Journal of Pharmacology, Volume 183, Issue 3, Page 435-437, February 2026.
Nikita Gamper
wiley   +1 more source

Protocol to study electrophysiological properties of hPSC-derived 3D cardiac organoids using MEA and sharp electrode techniques

open access: yesSTAR Protocols
Summary: Continuing advancements in human pluripotent stem cell (hPSC)-derived complex three-dimensional (3D) cardiac tissues require the development of novel technologies or adaptation of existing technologies to understand the physiology of the derived
Ravichandra Venkateshappa   +6 more
doaj   +1 more source

Low dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus.

open access: yesPLoS ONE, 2012
The anesthetic excitement phase occurring during induction of anesthesia with volatile anesthetics is a well-known phenomenon in clinical practice. However, the physiological mechanisms underlying anesthetic-induced excitation are still unclear.
Klaus Becker   +6 more
doaj   +1 more source

Social Interaction and Cocaine Conditioning in Mice Increase Spontaneous Spike Frequency in the Nucleus Accumbens or Septal Nuclei as Revealed by Multielectrode Array Recordings

open access: yesPharmacology, 2015
Both cocaine and social interaction place preference conditioning lead to increased neuronal expression of the immediate early gene EGR1 in the nucleus accumbens, a central region of the reward pathway, suggesting that both drug and natural rewards may ...
K. Kummer   +4 more
semanticscholar   +1 more source

Electro-gene transfer to skin using a noninvasive multielectrode array

open access: yesJournal of Controlled Release, 2011
Because of its large surface area and easy access for both delivery and monitoring, the skin is an attractive target for gene therapy for cutaneous diseases, vaccinations and several metabolic disorders. The critical factors for DNA delivery to the skin by electroporation (EP) are effective expression levels and minimal or no tissue damage.
Guo, Siqi   +5 more
openaire   +4 more sources

Flexible Multielectrode Arrays Based Electrochemical Aptasensor for Glycated Human Serum Albumin Detection

open access: green, 2023
Lei Zhou   +9 more
openalex   +1 more source

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