Results 111 to 120 of about 1,300,615 (222)

Human Stem Cell-Derived Neural Organoids for the Discovery of Antiseizure Agents

Receptors
Background: The development of cerebral organoids created from human pluripotent stem cells in 3D culture may greatly improve the discovery of neuropsychiatric medicines.
Hamed Salmanzadeh, Robert F. Halliwell
doaj   +1 more source

Assessment of Murine Retinal Acuity Ex Vivo Using Multielectrode Array Recordings. [PDF]

Transl Vis Sci Technol, 2023
Babino D, Benster T, Laprell L, Van Gelder RN.   +3 more
europepmc   +1 more source

Safety and feasibility of a novel multielectrode array catheter in mapping atrial and ventricular arrhythmias with high density: results from the multicenter OPTIMUM study. [PDF]

J Interv Card Electrophysiol, 2023
Vijgen J, Račkauskas G, Dilling-Boer D, Sarkozy A, Ciconte G, Vicedomini GG, Pappone C.   +6 more
europepmc   +1 more source

Delayed Repolarization Caused by hERG Block With Different Drug Modalities Can Be Detected in Stem Cell‐Derived Cardiomyocytes: Incubation Time Matters

Clinical and Translational Science
The intrinsic characteristics of oligonucleotides pose a challenge for their assessment in conventional primary in vitro cardiac models, which were designed for the acute application of small molecule agents and are not suitable for transfection and ...
Yusheng Qu, Wei Guo, Bin Wu, Jixin Cui, BaoXi Gao, Jill V. Nichols, Hugo M. Vargas   +6 more
doaj   +1 more source

Protocol to derive postganglionic parasympathetic neurons using human pluripotent stem cells for electrophysiological and functional assessment

STAR Protocols
Summary: Accessing untransformed human primary parasympathetic neurons is extremely challenging due to their inaccessibility in patients. Therefore, a human pluripotent stem cell-based approach to generate pure parasympathetic neurons is valuable for ...
Christina James, Hsueh-Fu Wu, Jennifer Art, Archie Patel, Nadja Zeltner   +4 more
doaj   +1 more source

High-Throughput Analysis of Drug Safety Responses in Induced Pluripotent Stem Cell-Derived Cardiomyocytes Using Multielectrode Array. [PDF]

Methods Mol Biol, 2022
Belbachir N, Cunningham N, Wu JC.
europepmc   +1 more source

Microstimulation of primary afferent neurons in the L7 dorsal root ganglia using multielectrode arrays in anesthetized cats: thresholds and recruitment properties

, 2009
Robert A. Gaunt, Jim Hokanson, Douglas J. Weber   +2 more
openalex   +1 more source

Neurotoxicity assessment of fluoxetine using multielectrode array recordings of human iPSC-derived neurons

, 2023
Yukuto Yasuhiko, Mana Murakami, Yasunari Kanda   +2 more
openalex   +2 more sources

Differential Subclinical Hemolysis After Pulsed Field Ablation Using the FARAPULSE Pentaspline Catheter Versus the PulseSelect Circular Multielectrode Array Catheter [PDF]

Setsuo Kuraoka, Masatsugu Nozoe, Hiroshi Mannoji, Ryo Miyake, Tomoki Uchikawa, Akihito Ishikita, Daisuke Nagatomo, Nobuhiro Suematsu, Toru Kubota   +8 more
openalex   +1 more source

Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice

Neurobiology of Disease
C. Jonak, Samantha A. Assad, Terese A. Garcia, Manbir S. Sandhu, J. Rumschlag, K. Razak, D. Binder   +6 more
semanticscholar   +1 more source