Results 41 to 50 of about 1,291,062 (187)

3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics

Nature Communications, 2021
Currently technologies for monitoring and controlling neural activities in 3D models are lacking. Here the authors report a 3D high-density multielectrode array, with optical stimulation and drug delivery, to investigate neural circuit dynamics in ...
Hyogeun Shin, Sohyeon Jeong, Ju-Hyun Lee, Woong Sun, Nakwon Choi, Il-Joo Cho   +5 more
doaj   +1 more source

Microelectronics, bioinformatics and neurocomputation for massive neuronal recordings in brain circuits with large scale multielectrode array probes

Brain Research Bulletin, 2015
Alessandro Maccione, Mauro Gandolfo, Stefano Zordan, Hayder Amin, Stefano Di Marco, Thierry Nieus, Gian Nicola Angotzi, Luca Berdondini   +7 more
openalex   +3 more sources

Patch-clamp and multi-electrode array electrophysiological analysis in acute mouse brain slices

STAR Protocols, 2021
Summary: Patch-clamp and multi-electrode array electrophysiology techniques are used to measure dynamic functional properties of neurons. Whole-cell and cell-attached patch-clamp recordings in brain slices can be performed in voltage-clamp and current ...
Kevin M. Manz, Justin K. Siemann, Douglas G. McMahon, Brad A. Grueter   +3 more
doaj   +1 more source

Assessment of Drug Proarrhythmic Potential in Electrically Paced Human Induced Pluripotent Stem Cell–Derived Ventricular Cardiomyocytes Using Multielectrode Array

SLAS discovery : advancing life sciences R & D, 2020
Human induced pluripotent stem cell–derived cardiomyocytes (hiPSC-CMs) have been widely used for the assessment of drug proarrhythmic potential through multielectrode array (MEA).
Shuyun Bai, Junjie Pei, Kan Chen, Ya Zhao, Henghua Cao, L. Tian, Yue Ma, Haiheng Dong   +7 more
semanticscholar   +1 more source

Spiral-Shaped Piezoelectric MEMS Cantilever Array for Fully Implantable Hearing Systems

Micromachines, 2017
Fully implantable, self-powered hearing aids with no external unit could significantly increase the life quality of patients suffering severe hearing loss.
Péter Udvardi, János Radó, András Straszner, János Ferencz, Zoltán Hajnal, Saeedeh Soleimani, Michael Schneider, Ulrich Schmid, Péter Révész, János Volk   +9 more
doaj   +1 more source

Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillations

Frontiers in Neuroscience, 2023
Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy.
Elysandra M. Solis, Levi B. Good, Levi B. Good, Levi B. Good, Rafael Granja Vázquez, Sourav Patnaik, Ana G. Hernandez-Reynoso, Qian Ma, Qian Ma, Gustavo Angulo, Gustavo Angulo, Aksharkumar Dobariya, Aksharkumar Dobariya, Stuart F. Cogan, Joseph J. Pancrazio, Juan M. Pascual, Juan M. Pascual, Juan M. Pascual, Juan M. Pascual, Juan M. Pascual, Vikram Jakkamsetti, Vikram Jakkamsetti   +21 more
doaj   +1 more source

Selective electrical stimulation with current-field modulation

Current Directions in Biomedical Engineering, 2021
Selective electrical stimulation using a multielectrode array is a promising technique that can potentially bring electrical stimulation treatment modalities a step forward.
Kárason Halldór, Pilkington Óskar, Helgason Thordur   +2 more
doaj   +1 more source

Long-term relationships between cholinergic tone, synchronous bursting and synaptic remodeling. [PDF]

PLoS ONE, 2012
Cholinergic neuromodulation plays key roles in the regulation of neuronal excitability, network activity, arousal, and behavior. On longer time scales, cholinergic systems play essential roles in cortical development, maturation, and plasticity ...
Maya Kaufman, Michael A Corner, Noam E Ziv   +2 more
doaj   +1 more source

New technology in experimental neurobiology: neuronal networks coupled with multielectrode array

Анналы клинической и экспериментальной неврологии, 2017
Multielectrode arraуs (MEA) as the recording and stimulatingsystem for self-organizing, functionally heterogeneous neuronalnetwork formed by developing CNS cells in vitro is a new, uniquetechnology for investigation of mechanisms of pathological ...
I. V. Mukhina, L. G. Khaspekov
doaj   +1 more source

A low-cost interface for multi-electrode array data acquisition systems

BioTechniques, 2008
Multi-electrode array systems have enabled the in vitro electrophysiological study of neuronal networks. The data processing component of these systems consists of an advanced computer system and data acquisition electronics that collectively cost more ...
Michael Serra, Amy Chan, Maya Dubey, Thomas B. Shea   +3 more
doaj   +1 more source