Results 251 to 260 of about 6,596,782 (296)

Role of Multienzyme Complexes in the Integration of Cellular Metabolism

Journal of Theoretical Biology, 1988
A large number of degradation processes provide the energetic needs of the living organism and its need of “building materials.” The synthesis of biomacromolecules is a result of numerous biosynthetic reactions. The striking peculiarity of the living system lies in the existence of rather fine and effective regulatory mechanisms that bring each ...
B. Kurganov
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Efficient Production of 2'-Fucosyllactose from l-Fucose via Self-Assembling Multienzyme Complexes in Engineered Escherichia coli.

ACS Synthetic Biology, 2021
2'-Fucosyllactose (2'-FL) has been widely used as a nutritional additive in infant formula due to its multifarious nutraceutical and pharmaceutical functions in neonate health.
L. Wan, Yingying Zhu, Geng Chen, Guocong Luo, Wenli Zhang, W. Mu   +5 more
semanticscholar   +1 more source

Nature Inspired Multienzyme Immobilization: Strategies and Concepts.

ACS Applied Bio Materials, 2021
In a biological system, the spatiotemporal arrangement of enzymes in a dense cellular milieu, subcellular compartments, membrane-associated enzyme complexes on cell surfaces, scaffold-organized proteins, protein clusters, and modular enzymes have ...
N. Dubey, B. Tripathi
semanticscholar   +1 more source

Research progress and the biotechnological applications of multienzyme complex

Applied Microbiology and Biotechnology, 2021
The multienzyme complex system has become a research focus in synthetic biology due to its highly efficient overall catalytic ability and has been applied to various fields. Multienzyme complexes are formed by cascading complexes, which are multiple functionally related enzymes that continuously and efficiently catalyze the production of substrates ...
Yi Jiang, Xinyi Zhang, Haibo Yuan, Di Huang, Ruiming Wang, Hongling Liu, Tengfei Wang   +6 more
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Multienzyme complex for carbon dioxide fixation

Biochemistry, 1975
Acetyl-coenzyme A carboxylase from Euglena gracilis strain Z was isolated as a component of a multienzyme complex which includes phosphoenolpyruvate carboxylase and malate dehydrogenase. The multienzyme complex was shown to exist in crude extracts and was purified to a homogeneous protein with a molecular weight of 360,000 by gel filtration.
Mary Lou Ernst-Fonberg, Jack S. Wolpert
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A Multienzyme Bioreactor Based on a Chitinase Complex

Прикладная биохимия и микробиология, 2014
A heterogeneous biocatalyst containing a complex of chitinolytic enzymes isolated from the culture medium of bacteria Clostridium paraputrificum on the surface of macroporous monolithic minidisc was obtained. The complex of chitinolytic enzymes was immobilized on the polymer matrix using a multistep method involving the introduction of an intermediate ...
Tatiana B. Tennikova, Tatiana B. Tennikova, E. A. Ponomareva, E. G. Vlakh, E. G. Vlakh   +4 more
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The pyruvate dehydrogenase multienzyme complex

Current Opinion in Structural Biology, 1992
Abstract During the review period, several structures of component enzymes and domains of enzymes of this multienzyme complex were determined. Three structures of the flavoprotein component, dihydrolipoamide dehydrogenase, became available. The structure of the core component, dihydrolipoyl acetyltransferase, can in principle be constructed from the ...
Richard N. Perham, Aart de Kok, Andrea Mattevi   +2 more
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Regulation of the Pyruvate Dehydrogenase Multienzyme Complex

Annual Review of Nutrition, 1993
To maximize catalytic efficiency in metabolic pathways of both prokaryotic and eUkaryotic cells, enzymatic components are occasionally clustered or complexed physically. Organization of multiple catalytic functions into a single enzyme complex can be accomplished in two ways.
Denis B. Buxton, R. H. Behal, Merle S. Olson, J. G. Robertson   +3 more
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[41] Purification of multienzyme complexes

1990
Publisher Summary This chapter discusses the use of enzymes of nucleotide metabolism to illustrate procedures for the purification and characterization or multi-enzyme complexes. A significant result of these procedures is the successful use of ammonium sulfate precipitation to concentrate and enrich each of the three complexes.
Christopher K. Mathews, Paul A. Srere
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The Pyruvate Dehydrogenase Multienzyme Complex

Angewandte Chemie International Edition in English, 1975
AbstractThe three enzymes pyruvate dehydrogenase, dihydrolipoamide transacetylase, and dihydrolipoamide dehydrogenase constitute the pyruvate dehydrogenase multienzyme complex of E. coli; in mammals the complex also contains a kinase and a phosphatase.
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