Results 251 to 260 of about 6,631,648 (289)

Lysosomal multienzyme complex: Biochemistry, genetics, and molecular pathophysiology

2001
Lysosomal enzymes sialidase (alpha-neuraminidase), beta-galactosidase, and N-acetylaminogalacto-6-sulfate sulfatase are involved in the catabolism of glycolipids, glycoproteins, and oligosaccharides. Their functional activity in the cell depends on their association in a multienzyme complex with lysosomal carboxypeptidase, cathepsin A.
A V, Pshezhetsky, M, Ashmarina
openaire   +2 more sources

A Multienzyme Complex for De Novo Purine Biosynthesis

1977
Multienzyme complexes are defined as aggregates of different functionally related enzymes integrated into highly organized structures by non-covalent bonds. Such a structural arrangement is considered to confer a catalytic advantage in that an unstable intermediate may be transferred more efficiently from one active site to the next.
P B, Rowe, G, Madsen, E, McCairns, D, Sauer   +3 more
openaire   +2 more sources

[Structure-activity relationships in multienzyme complexes].

Molekuliarnaia biologiia, 1996
Structures and molecular kinetic models of function of 2-oxo acid dehydrogenase complexes were analyzed. It was suggested that identical protein subunits in the multienzyme complexes as in the structure capable of self-assembly have identical contacts with the neighbors and identical environment.
B N, Gol'dshteĭn, S R, Saĭfullin, D T, Zakrzhevskaia   +2 more
openaire   +1 more source

Evidence supporting multienzyme complexes as metabolons: A review

International Journal of Biological Macromolecules
Fungi are widespread organisms with complex multienzyme systems crucial for diverse biochemical processes. This study systematically reviewed research on multienzyme complexes, focusing on their isolation and identification, while examining their potential classification as metabolons.
Hebah, Al-Tamimi, Aidil Abdul, Hamid, Mohamed Yusuf Mohamed, Nazir, Maizom, Hassan, Izyanti, Ibrahim   +4 more
openaire   +2 more sources

Directed regulation of multienzyme complexes of 2-oxo acid dehydrogenases using phosphonate and phosphinate analogs of 2-oxo acids

Biochemistry (Moscow), 2016
A. Artiukhov, A. Graf, V. Bunik
semanticscholar   +1 more source

A multienzyme complex for CO2 fixation.

Biochemistry, 1975
Acetyl-coenzyme A carboxylase from Euglena gracilis strain Z was isolated as a component of a multienzyme complex which includes phosphoenolpyruvate carboxylase and malate dehydrogenase. The multienzyme complex was shown to exist in crude extracts and was purified to a homogeneous protein with a molecular weight of 360,000 by gel filtration.
J S, Wolpert, M L, Ernst-Fonberg
openaire   +1 more source

A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery.

Biochimica et Biophysica Acta, 2013
R. Nussinov, B. Ma, Chung-Jung Tsai
semanticscholar   +1 more source

Proteomic analysis in non-denaturing condition of the secretome reveals the presence of multienzyme complexes in Penicillium purpurogenum

Applied Microbiology and Biotechnology, 2010
A. Gonzalez-Vogel, J. Eyzaguirre, G. Oleas, E. Callegari, Mario Navarrete   +4 more
semanticscholar   +1 more source

Valorization of Residual Agroindustrial Cakes by Fungal Production of Multienzyme Complexes and Their Use in Cold Hydrolysis of Raw Starch

, 2011
A. Castro, Thiago Vetter Andréa, Daniele Fernandes Carvalho, M. M. Teixeira, Leda Reis Castilho, D. Freire   +5 more
semanticscholar   +1 more source

Crystal structure of 2-oxoisovalerate and dehydrogenase and the architecture of 2-oxo acid dehydrogenase multienzyme complexes

Nature Structural Biology, 1999
Arnthór Ævarsson, K. Seger, S. Turley, J. R. Sokatch, W. Hol   +4 more
semanticscholar   +1 more source