Results 111 to 120 of about 17,949 (246)

The interplay between dynamic regulation of ion‐channel gating and trafficking in cardiac arrhythmogenesis

The Journal of Physiology, EarlyView.
Abstract figure legend Cardiac cellular electrophysiology is modulated by multiple factors, including temperature, extracellular K+, heart rate/pacing frequency, and drugs. These modulators can have distinct effects on ion‐channel gating and transcription/trafficking over time.
Stefan Meier, Anna S. Savchenko, Paul G. A. Volders, Jordi Heijman   +3 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Genetics of epilepsy. [PDF]

Exp Biol Med (Maywood)
Piacentini K, Gaitatzis A, Kõks S.
europepmc   +1 more source

Law and Ethics of Nanotechnology: Traditional Legal Tools Advancing Nanomedicine

physica status solidi (a), Volume 223, Issue 15, 5 August 2026.
Science fiction from the last decades is rapidly becoming science in daily life. For example, nanotechnology does cool things like creating driverless cars for people who are blind and storing solar energy to drive electric cars. Nanotechnology makes possible 3D printing of housing, clothing, and food and miraculous treatments for previously incurable ...
Ilise Feitshans
wiley   +1 more source

Thromboinflammatory biomarkers in obstetric pathophysiology: Predictive insights into placental insufficiency and feto‐maternal adverse outcomes

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Placental insufficiency is a thromboinflammatory disorder driven by angiogenic imbalance, complement activation, endothelial dysfunction and coagulation dysregulation, leading to microvascular thrombosis, impaired uteroplacental perfusion and adverse maternal and fetal outcomes, including pre‐eclampsia, fetal growth restriction and stillbirth. Abstract
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Genetic Epidemiological Analysis of the Keratoconus Genetic Model in the Chinese Keratoconus Cohort Study. [PDF]

Invest Ophthalmol Vis Sci
Yin S, Xu L, Yang K, Fan Q, Gu Y, Yin C, Zang Y, Wang Y, Yuan Y, Chang A, Li C, Pang C, Sahebjada S, Hao Y, Ren S.   +14 more
europepmc   +1 more source

Preliminary Validation of a Novel Genetic Knowledge Scale for Familial Hypercholesterolemia: Evaluation of Face Validity and Core Concepts

Journal of Genetic Counseling, Volume 35, Issue 4, August 2026.
ABSTRACT Facilitating patient‐informed decision making is central to the genetic counseling practice. The Multidimensional Model of Informed Choice (MMIC) evaluates informed decisions in genetic testing, but validated MMIC measures for inherited cardiac conditions are lacking.
Emily Moss, Jeffrey Wigle, Claudia Carriles‐Landry, Kim Mitchell, Hannah Wand, Jill Slamon, Roya Mostafavi, Amy Yonda, Susan Christian   +8 more
wiley   +1 more source

Special Issue "Human Traits and Genomics: An Integrative Perspective". [PDF]

Int J Mol Sci
Saccone S, Larizza L, Malerba G.
europepmc   +1 more source

Early‐Onset Prostate Cancer: Epidemiology, Risk Factors, Biology, Clinical Features, Management, and Early Detection

MedComm, Volume 7, Issue 8, August 2026.
EOPC is a distinct clinicopathological entity separable from SOPC, differing fundamentally in genetic susceptibility, TMPRSS2:ERG fusion frequency, and survival outcomes. Although research remains nascent, this review provides the first comprehensive synthesis of current evidence, offering a critical foundation to guide future investigations into this ...
Xingyu Xiong, Weizhen Zhu, Weichao Huang, Shiyu Zhang, Qi Deng, Jie Yang, Hang Xu, Qiang Wei, Lu Yang   +8 more
wiley   +1 more source

Rethinking areas of endemism and barriers: perspectives for a causal historical biogeography and a critique of Schultz and Cracraft (2024)

Cladistics, Volume 42, Issue 4, Page 401-412, August 2026.
Abstract Historical biogeography faces a persistent conceptual and methodological dilemma concerning the nature of its central analytical units. Using the recent proposal by Schultz and Cracraft (Cladistics 40, 653) as a catalyst, this article critiques the argument that causal inference necessitates the replacement of areas of endemism with barriers ...
Augusto Ferrari
wiley   +1 more source