Results 121 to 130 of about 229,156 (260)

PATH-38. ROSETTE-FORMING GLIONEURONAL TUMOR IS DEFINED BY FGFR1 ACTIVATING ALTERATIONS WITH FREQUENT ACCOMPANYING PI3K AND MAPK PATHWAY MUTATIONS [PDF]

, 2019
BACKGROUND Rosette-forming glioneuronal tumor (RGNT) is an uncommon CNS tumor originally described in the fourth ventricle characterized by a low-grade glial neoplasm admixed with a rosette-forming neurocytic component.
Aghi, Manish, Ann Oberheim-Bush, Nancy, Banerjee, Anu, Bannykh, Serguei, Berger, Mitchel, Bollen, Andrew, Born, Donald, Brathwaite, Carole, Buerki, Robin, Butowski, Nicholas, Calixto-Hope, Lucas, Chamyan, Gabriel, Chang, Susan, Clarke, Jennifer, Cooney, Tabitha, Devine, Patrick, Fata, Cynthia, Grafe, Marjorie, Grenert, James, Guo, Hua, Gupta, Nalin, Hervey-Jumper, Shawn, Hofmann, Jeffrey, Jin, Lee-way, Khatib, Ziad, Kleinschmidt-DeMasters, Bette, Kline, Cassie, Lechpammer, Mirna, Lee, Han, Lee, Julieann, Maher, Ossama, McDermott, Mike, Onodera, Courtney, Pekmezci, Melike, Pelaez, Liset, Perry, Arie, Phillips, Joanna, Raffel, Corey, Samuel, David, Scharnhorst, David, Sloan, Emily, Solomon, David, Sun, Peter, Taylor, Jennie, Theodosopoulos, Philip, Tihan, Tarik, Torkildson, Joseph, Van Ziffle, Jessica, Vogel, Hannes, Wood, Matthew   +49 more
core  

Surgical Technique for Treating Focal Osteochondral Knee Lesions Using an Aragonite‐Based Biphasic Scaffold

Arthroscopy Techniques, EarlyView.
Abstract Osteochondral lesions of the knee, particularly in patients with early osteoarthritic changes, remain a clinical challenge. The Agili‐C implant (CartiHeal, Smith & Nephew), an aragonite‐based osteochondral scaffold, offers a single‐stage, off‐the‐shelf solution designed to regenerate both cartilage and subchondral bone.
Eric Wang, Alexandra M. Cancio‐Bello, Katelyn T. Koschmeder, Bryn Berens, Anikar Chhabra   +4 more
wiley   +1 more source

The percutaneous treatment of Patent Foramen Ovale, an effective and safe therapeutic choice

Open Medicine, 2013
Evola S., Trovato R., Kauroo B., Alioto L., Sucato V., Quagliana A., Magro S., Tona R., Novo G., Andolina G., Assennato P., Novo S.   +11 more
doaj   +1 more source

Visual Outcomes, Visual Quality and Patient Satisfaction: Comparing a Blended Bifocal Approach to Bilateral Extended Depth of Focus Intraocular Lens Implantation

Clinical Ophthalmology, 2019
Matthew D Hammond,1 Richard Potvin2 1Swagel Wootton Eye Institute, Mesa, AZ, USA; 2Science in Vision, Akron, NY, USACorrespondence: Richard Potvin 6197 Dye Road, Akron, NY 14001, USATel +1 407-697-6008Email rick@scienceinvision.comPurpose: To compare ...
Hammond MD, Potvin R
doaj  

Causes of mortality and characterisation of Mycobacteriosis in adult New Zealand sea lions (Phocarctos Hookeri) at Enderby Island : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Science in Wildlife Health at Massey University, Manawatū, Palmerston North, New Zealand [PDF]

, 2017
The New Zealand sea lion (Phocarctos hookeri) is classified as endangered and “Nationally Critical” due to a declining population and restricted population range. There have been recent bacterial epizootic events at the breeding colonies of this species,
Lenting, Baukje Mirjam
core  

Early‐stage health technology assessment of a curative gene therapy for multiple sclerosis

British Journal of Clinical Pharmacology, EarlyView.
Aims Multiple sclerosis (MS) is associated with significant early morbidity, reduced life expectancy and substantial healthcare and societal costs. The primary objective of this study is to assess the early cost‐effectiveness potential of a novel gene therapy, IMMUTOL, for MS compared with current high‐efficacy treatment sequences.
Attila Imre, Balázs Nagy, Rok Hren
wiley   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

British Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse, Christophe Hommel, Nadine Petitpain, Philippe Kerschen   +3 more
wiley   +1 more source

Pt‐TiO2 mesoporous nanosystem co‐delivering phlorezin enables synergistic sonodynamic‐chemoimmunotherapy for hepatocellular carcinoma via directly targeting DDX5 and metabolic reprogramming modulation

BMEMat, EarlyView.
Abstract Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer‐related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt‐TiO2 nanoparticles for the co‐delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic ...
Kairui Liu, Bo Zhang, Yue Wan, Zhiru Yang, Abdusami Abdurahman, Mengxin He, Shengtao Hu, Yi Zhang, Xiaoke Li, Jin Chang, Jun Kang, Liren Liu, Wanghua Liu, Shao Li   +13 more
wiley   +1 more source

Objective perimetry and diabetic retinopathy progression: a 10-year follow-up study

Frontiers in Endocrinology
PurposeWe investigated 10-year retinal function changes in persons with type 2 diabetes (PWT2D) using the objectiveFIELD Analyser (OFA) to measure per-region sensitivity and response delay.
Betelhem T. Yibekal, Bhim B. Rai, Joshua P. van Kleef, Faran Sabeti, Faran Sabeti, Emilie M. F. Rohan, Christopher J. Nolan, Christopher J. Nolan, Ted Maddess   +8 more
doaj   +1 more source

Neonatal Seizures in Tuberous Sclerosis Complex: A Case Series

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Epilepsy affects up to 90% of patients with tuberous sclerosis complex (TSC); earlier seizure onset is associated with worse neurocognitive outcomes. The incidence of neonatal seizures in TSC is unknown, although in a recent multicenter trial 23% of infants with TSC were excluded prior to randomization because of pre‐existing ...
Kristina Jülich, Kristen Arredondo
wiley   +1 more source