Results 31 to 40 of about 1,269,464 (343)

Fabrication of multifunctional metal–organic frameworks nanoparticles via layer-by-layer self-assembly to efficiently discover PSD95-nNOS uncouplers for stroke treatment

open access: yesJournal of Nanobiotechnology, 2022
Background Disruption of the postsynaptic density protein-95 (PSD95)—neuronal nitric oxide synthase (nNOS) coupling is an effective way to treat ischemic stroke, however, it still faces some challenges, especially lack of satisfactory PSD95-nNOS ...
Yingying Ding   +9 more
doaj   +1 more source

Affinity Purification of Multifunctional Polymer Nanoparticles [PDF]

open access: yesJournal of the American Chemical Society, 2010
We report that multifunctional polymer nanoparticles approximately the size of a large protein can be "purified", on the basis of peptide affinity just as antibodies, using an affinity chromatography strategy. The selection process takes advantage of the thermoresponsiveness of the nanoparticles allowing "catch and release" of the target peptide by ...
Yu, Hoshino   +5 more
openaire   +2 more sources

Molecular Imaging with Multifunctional Nanoparticles [PDF]

open access: yesClinical Chemistry, 2013
Featured Article: Gao XH, Cui YY, Levenson RM, Chung LWK, Nie SM. In vivo cancer targeting and imaging with semiconductor quantum dots. Nat Biotechnol 2004;22:969–76.2 The development of high-sensitivity and high-specificity probes that transcend the intrinsic limitations of organic fluorophores has been highly sought after by scientists in fields ...
openaire   +2 more sources

Surface-modified multifunctional MIP nanoparticles [PDF]

open access: yesNanoscale, 2013
The synthesis of core-shell molecularly imprinted polymer nanoparticles (MIP NPs) has been performed using a novel solid-phase approach on immobilised templates. The same solid phase also acts as a protective functionality for high affinity binding sites during subsequent derivatisation/shell formation.
Moczko, Ewa   +7 more
openaire   +3 more sources

Nanoparticle-functionalized microcapsules for in vitro delivery and sensing

open access: yesNanophotonics, 2012
Inorganic nanoparticles such as magnetic nanoparticles, fluorescent quantum dots, and plasmonic nanoparticles can be used as building blocks for designing multifunctional systems based on polymeric capsules.
Carregal-Romero Susana   +2 more
doaj   +1 more source

Smart multifunctional nanoparticles in nanomedicine

open access: yes, 2016
Recent advances in nanotechnology caused a growing interest using nanomaterials in medicine to solve a number of issues associated with therapeutic agents.
M. Şeleci   +5 more
semanticscholar   +3 more sources

Gold nanoparticles explore cells: cellular uptake and their use as intracellular probes [PDF]

open access: yes, 2014
Understanding uptake of nanomaterials by cells and their use for intracellular sensing is important for studying their interaction and toxicology as well as for obtaining new biological insight.
Septiadi, Dedy   +7 more
core   +1 more source

Targeted Molecular Imaging of Pancreatic Cancer with a Miniature Endoscope

open access: yesApplied Sciences, 2017
It is highly desirable to develop novel approaches to improve patient survival rate of pancreatic cancer through early detection. Here, we present such an approach based on photoacoustic and fluorescence molecular imaging of pancreatic tumor using a ...
Xianjin Dai   +4 more
doaj   +1 more source

Safety and Toxicity Implications of Multifunctional Drug Delivery Nanocarriers on Reproductive Systems In Vitro and In Vivo

open access: yesFrontiers in Toxicology, 2022
In the recent past, nanotechnological advancements in engineered nanomaterials have demonstrated diverse and versatile applications in different arenas, including bio-imaging, drug delivery, bio-sensing, detection and analysis of biological ...
Anas Ahmad, Anas Ahmad
doaj   +1 more source

Synthesis of Multifunctional Amorphous Metallic Shell on Crystalline Metallic Nanoparticles

open access: yes, 2022
Colloidal nanoparticles can be coated with a conformal shell to form multifunctional nanoparticles. For instance, plasmonic, magnetic, and catalytic properties, chemical stability and biocompatibility can be mixed and matched.
Abhinav, Parakh   +6 more
core   +1 more source

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