Results 131 to 140 of about 1,322,987 (378)

Protein covariation networks for elucidating ferroptosis inducer mechanisms and potential synergistic drug targets

Communications Biology
In drug development, systematically characterizing a compound’s mechanism of action (MoA), including its direct targets and effector proteins, is crucial yet challenging.
Rina Kunishige, Yoshiyuki Noguchi, Naomi Okamoto, Lei Li, Akito Ono, Masayuki Murata, Fumi Kano   +6 more
doaj   +1 more source

Learning-Based Discontinuous Path Following Control for a Biomimetic Underwater Vehicle

Research
This paper addresses a learning-based discontinuous path following control scheme for a biomimetic underwater vehicle (BUV) driven by undulatory fins. Despite the flexibility of the BUV motion, it faces the challenge of dealing with discontinuous paths ...
Yu Wang, Hongfei Chu, Ruichen Ma, Xuejian Bai, Long Cheng, Shuo Wang, Min Tan   +6 more
doaj   +1 more source

From Wafers to Electrodes: Transferring Automatic Optical Inspection (AOI) for Multiscale Characterization of Smart Battery Manufacturing

Advanced Functional Materials, EarlyView.
Automat optical inspection (AOI) techniques in semiconductor fabrication can be leveraged in battery manufacturing, enabling scalable detection and analysis of electrode‐ and cell‐level imperfections through AI‐driven analytics and a digital‐twin framework.
Jianyu Li, Ertao Hu, Wei Wei, Feifei Shi
wiley   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Bio‐Inspired Multimodal Hardware Front‐End Enabled by 2D Floating‐Gate Memory for UAV Perception

Advanced Functional Materials, EarlyView.
A MoS2/h‐BN /graphene floating‐gate memory underpins a bio‐inspired multimodal front end that integrates visual, inertial, and airflow cues. A 4 × 4 FG memory array encodes temporal intensity differences, while IMU‐ and airflow‐driven threshold modulation suppresses self‐motion artifacts, enabling fast, low‐power, robust autonomous UAV tracking and ...
Lianghao Guo, Yue Cheng, Cong Li, Xiaoyu Guo, Jiankai Yin, Dadong Fan, Zhenyu Xu, Chenyu Tang, Arokia Nathan, Shuo Gao, Li Tao, Luigi G. Occhipinti   +11 more
wiley   +1 more source

Contracted functional connectivity profiles in autism

Molecular Autism
Objective Autism spectrum disorder (ASD) is a neurodevelopmental condition that is associated with atypical brain network organization, with prior work suggesting differential connectivity alterations with respect to functional connection length.
Clara F. Weber, Valeria Kebets, Oualid Benkarim, Sara Lariviere, Yezhou Wang, Alexander Ngo, Hongxiu Jiang, Xiaoqian Chai, Bo-yong Park, Michael P. Milham, Adriana Di Martino, Sofie Valk, Seok-Jun Hong, Boris C. Bernhardt   +13 more
doaj   +1 more source

Regulated Ion‐Diffusion Hydrogels for Subtle and Multimodal Temperature‐Strain Sensing in Wound Monitoring

Advanced Functional Materials, EarlyView.
A soft, dual‐channel hydrogel patch enables simultaneous detection of wound temperature and strain by integrating ion‐diffusion‐mediated thermoelectric and resistive sensing. The conformal design maintains stable performance during motion, capturing subtle inflammatory and mechanical changes for continuous wound monitoring.
Yu Fang, Xinglong Pan, Zhiwei Li, Wanheng Lu, Chang Liu, Yi Zhou, Guo Tian, Ghim Wei Ho   +7 more
wiley   +1 more source

Fast mass spectrometry imaging for immunohistochemistry [PDF]

BIO Web of Conferences
Shamraeva Mariya, Sandström Edith, Garcia Kimberly G., Heeren Ron M. A., Anthony Ian G. M., van Nuffel Sebastiaan   +5 more
doaj   +1 more source

A multimodal generative AI copilot for human pathology

Nature
Computational pathology1,2 has witnessed considerable progress in the development of both task-specific predictive models and task-agnostic self-supervised vision encoders3,4.
Ming Y. Lu, Bowen Chen, Drew F. K. Williamson, Richard J. Chen, Melissa Zhao, Aaron K Chow, Kenji Ikemura, Ahrong Kim, Dimitra Pouli, Ankush U Patel, Amr Soliman, Chengkuan Chen, Tong Ding, Judy J. Wang, Georg K. Gerber, Ivy Liang, L. Le, Anil V Parwani, Luca L. Weishaupt, Faisal Mahmood   +19 more
semanticscholar   +1 more source