Results 161 to 170 of about 419,255 (384)

Postoperative Multimodal Approach to Pain Control in Anterior Cruciate Ligament Autograft Surgery: A Single-Center Series

Surgeries
Background: Anterior cruciate ligament (ACL) injuries are prevalent and represent a significant socioeconomic burden, as ACL injuries account for nearly 60% of all knees joint traumas.
Alexey Cheykin, Evgeniy Nikolaevich Goncharov, Oleg Aleksandrovich Koval, Nikolay Goncharov, Eduard Bezuglov, Aleksandr Vetoshkin, Manuel De Jesus Encarnacion Ramirez, Nicola Montemurro   +7 more
doaj   +1 more source

BioTD: an online database of biotoxins [PDF]

arXiv
Biotoxins, mainly produced by venomous animals, plants and microorganisms, exhibit high physiological activity and unique effects such as lowering blood pressure and analgesia. A number of venom-derived drugs are already available on the market, with many more candidates currently undergoing clinical and laboratory studies.
arxiv  

How can we reduce healthcare costs by using Enhanced Recovery After Surgery more effectively in different groups of gynaecological patients? A single‐centre experience

Journal of Evaluation in Clinical Practice, Volume 31, Issue 3, April 2025.
Abstract Introduction The objective of this study was to assess the impact of the Enhanced Recovery After Surgery (ERAS) programme implementation on treatment costs at a university‐type centre, using the DRG scheme. Materials and Methods Retrospective analysis of patients' data in a group of 604 individuals enroled in the study.
Markéta Polková, Peter Koliba, Pavel Kabele, Oľga Dubová, Daniel Hodyc, Magdalena Kolínková Škodová, Michal Zikán, Petra Sládková, Marie Tichá, Tomáš Brtnický   +9 more
wiley   +1 more source

Deciphering the unique dynamic activation pathway in a G protein-coupled receptor enables unveiling biased signaling and identifying cryptic allosteric sites in conformational intermediates [PDF]

arXiv
Neurotensin receptor 1 (NTSR1), a member of the Class A G protein-coupled receptor superfamily, plays an important role in modulating dopaminergic neuronal activity and eliciting opioid-independent analgesia. Recent studies suggest that promoting \{beta}-arrestin-biased signaling in NTSR1 may diminish drugs of abuse, such as psychostimulants, thereby ...
arxiv  

Pain Assessment and Management in Dementia Care: Qualitative Perspectives of People With Dementia, Their Families, and Healthcare Professionals

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim Pain is under‐assessed and under‐treated among people living with dementia. This study aims to explore the perspectives of people with dementia, family carers, and healthcare professionals regarding their experiences and needs for pain assessment and management. Design A qualitative descriptive approach. Methods Between May and August 2023,
Lihui Pu, Matthew Barton, Madushika Kodagoda Gamage, Mari Okada, Michael Todorovic, Wendy Moyle   +5 more
wiley   +1 more source

Confronting the opioid crisis: Practical pain management and strategies: AOA 2018 critical issues symposium [PDF]

, 2019
The United States is in the midst of an opioid crisis. Clinicians have been part of the problem because of overprescribing of narcotics for perioperative pain management.
Hsu, Joseph R, Jahangir, A Alex, Miller, Anna N, Mir, Hassan R, Obremskey, William T   +4 more
core   +1 more source

Beyond Depression: The Role of Antidepressants in Managing Chronic Temporomandibular Disorders. A Systematic Review

Journal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Chronic temporomandibular disorder (TMD) pain significantly impairs quality of life and lacks universally effective treatments. Antidepressants, traditionally used for mood disorders, have shown potential in managing chronic pain conditions.
Takara Dei, Kennedy Galloway, Nathalia Carolina Fernandes Fagundes, Janice Y. Kung, Nathan P. Beahm, Reid Friesen   +5 more
wiley   +1 more source

Internet‐Based Behavioural Therapy for Adolescents With Temporomandibular Disorder Pain: A Feasibility Multicenter Randomised Controlled Trial

Journal of Oral Rehabilitation, EarlyView.
ABSTRACT Background Temporomandibular disorder (TMD) pain in adolescents is common, has a negative impact on quality of life, and is a predictor of pain in young adulthood. A common and symptomatic treatment is occlusal appliance therapy (OAT). Internet‐based behavioural therapy (IBT) is a novel, multimodal, and patient‐centred self‐management therapy ...
Tessa Bijelic, Ing‐Marie Nilsson, Thomas List, EwaCarin Ekberg   +3 more
wiley   +1 more source

Thoracic Paravertebral Block, Multimodal Analgesia, and Monitored Anesthesia Care for Breast Cancer Surgery in Primary Lateral Sclerosis [PDF]

, 2016
Anis Dizdarevic, A.E. Ribeiro Fernandes
openalex   +1 more source

HTX-011 reduced pain intensity and opioid consumption versus bupivacaine HCl in bunionectomy: phase III results from the randomized EPOCH 1 study. [PDF]

, 2019
BACKGROUND AND OBJECTIVES: There is a need for local anesthetics that provide consistent analgesia through 72 hours after surgery. This study evaluates the use of HTX-011 (bupivacaine and meloxicam in Biochronomerpolymer technology), an extended-release,
Gimbel, Joseph S., Hu, Jia, Lee, Gwo-Chin, Pollack, Richard A., Viscusi, Eugene R.   +4 more
core   +1 more source