Results 161 to 170 of about 23,774 (296)

In silico prediction of novel effective combinational treatment of chronic pain in individual patients: A joint white paper of the H2020 QSPainRelief consortium

British Journal of Pharmacology, EarlyView.
Abstract Opioids are prescribed widely for chronic pain despite well‐recognised risks and variable long‐term benefit, reflecting the lack of effective alternatives for many patients. Combination therapies offer a promising strategy to enhance efficacy whilst reducing side effects.
André Mouraux, Solenn Gousset, Beltrán Alvarez, Monica Baiula, Wouter Bakker, Andrea Bedini, Monir Bertayli, Divakar Budda, Robert Carr, Elisabetta Cuna, Óscar Díaz, Nina Donner, Jesús Giraldo, Geert‐Jan Groeneveld, Berfin Gülave, David Guydan, Hemme Hijma, Rafael Maldonado, Pedro Renault, Carlos Rinaudo, Jeroen Elaissaiss‐Schaap, Athan Spiros, Sara Stoeber, Petri Takkala, Daan van Valkengoed, Coen van Hasselt, Elizabeth (Liesbeth) CM de Lange   +26 more
wiley   +1 more source

Multimodal Analgesia Provides Superior Postoperative Pain Control Following Orthopedic Surgery in Small-Breed Dogs. [PDF]

Animals (Basel)
Kim SH, Park S, Bae CS.
europepmc   +1 more source

Enhanced Recovery After Surgery Protocol in Transoral Robotic Surgery: A Case–Control Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction ‘Enhanced Recovery After Surgery’ (ERAS) protocols have been developed for multiple surgical procedures with favourable outcome measures including Length of Stay (LoS). Trans‐Oral Robotic Surgery (TORS) has similarly facilitated earlier patient discharges, particularly in comparison to open head and neck surgical techniques. There
Jonathan Daniel, Raguwinder Bindy Sahota, Mark David Wilkie, Lee Pryor, Ahmed Bassiouni, Jake Jervis‐Bardy, Arun Takhar, Bora Jeong, Oladejo Olaleye, Suren Krishnan, J. C. Hodge, Andrew Foreman   +11 more
wiley   +1 more source

Pilot Study: Evaluation of the Feasibility of a Multimodal Analgesia Protocol for Primary Breast Augmentation Patients. [PDF]

Plast Reconstr Surg Glob Open
Doherty CJ, Teitler NA, Samson KK, Meyer BR, Wong SL, Hon HH.   +5 more
europepmc   +1 more source

From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment

Cell Proliferation, EarlyView.
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang, Miao Xu, Yongshun Wang, Xuan Lin, Qiang Zhang, Xiaoning Lin, Xin Wu, Cheng Zhang, Wenhua Huang, Jianlin Shen   +9 more
wiley   +1 more source

Postoperative Care and Management in Pediatric Hematology‐Oncology Patients

European Journal of Haematology, EarlyView.
ABSTRACT Pediatric patients with hematologic and oncologic diseases often undergo surgical procedures as part of diagnosis and therapy. These include central venous catheter placements, tumor resections, lymph node and bone marrow biopsies, among others.
Shachi Srivatsa, Sara A. Mansfield
wiley   +1 more source

Analgesic effects of alpha‐2‐adrenoreceptor agonists in equine medicine: systemic, spinal, and local applications

Equine Veterinary Education, EarlyView.
Summary Alpha‐2‐adrenoreceptor agonists provide analgesia when used as sole agents but can also be used in combination with other drugs for their additive and potentially synergistic effects. Further, because of their effects on blood flow, alpha‐2‐adrenoreceptor agonists act to extend and perhaps intensify the effects of drugs, such as local ...
J. Brandly, J. R. Page, J. A. E. Hubbell, W. W. Muir III, K. Hopster   +4 more
wiley   +1 more source

Hypobaric unilateral spinal anesthesia with multimodal analgesia enhances recovery in total knee arthroplasty. [PDF]

BMC Anesthesiol
Meng X, Wang D, Liu X, Xia S, Zhang S, Wang W, Wu Y, Huang G.   +7 more
europepmc   +1 more source

Surgical removal of a perirectal melanoma through sphincterotomy and rectal wall resection in a horse

Equine Veterinary Education, EarlyView.
Summary Melanomas are among the most frequent neoplasms in grey horses. Deep perirectal melanomas, however, are uncommon and challenging to excise due to their proximity to the peritoneal reflection. This report describes the successful standing removal of a large (16 × 8 × 6 cm) perirectal melanoma firmly adherent to the dorsal rectal wall in a 19 ...
R. Becker, C. Koch, M. de Preux
wiley   +1 more source

Application of oxycodone in multimodal analgesia for thoracoscopic lung surgery: A single-center retrospective observational study. [PDF]

Medicine (Baltimore)
Zhang R, Fu Y, Zhang W, Wang X.
europepmc   +1 more source