Results 51 to 60 of about 32,845 (311)

Histologic Sequelae of Apical Hypertrophic Cardiomyopathy: Dystrophic Calcification

Clinical Medicine Insights: Cardiology, 2017
We present cardiac computed tomography (CT) findings demonstrating apical hypertrophic cardiomyopathy with dystrophic calcification of the left ventricular apex.
Shahryar G Saba, John N Makaryus, Navid Rahmani, Ram Jadonath   +3 more
doaj   +1 more source

Epicardial Fat Volume as a New Imaging-Based Feature Associated with Risk of Recurrence after Pulmonary Veins Ablation in Atrial Fibrillation

Journal of Interdisciplinary Medicine, 2020
Background: Atrial fibrillation (AF), a common arrhythmia in clinical practice, is associated with a high rate of complications and an increased risk for thromboembolic events.
Blîndu Emanuel, Korodi Szilamér, Bordi Lehel, Kovács István, Benedek Imre   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Rational and design of EACVI-MMVD study: an international registry on multimodality imaging for mixed and multiple valvular heart disease [PDF]

International audienceAims Multiple and mixed valvular heart disease (MMVD) are frequent situations in clinical practice. Despite a high prevalence, comprehensive insights into their clinical presentation, management strategies, impact of multimodality ...
Cosyns, B, Nijveldt, R, Vicaut, E, Cosyns, Bernard, Toupin, S, Muraru, D, Borodzicz-Jazdzyk, S, Romero Dorta, Elena, Timoteo, Ana Teresa, Clavel, Marie-Annick, Coisne, Augustin, Pezel, Théo, Mandoli, GE, Timoteo, AT, Nijveldt, Robin, Neglia, D, Ajmone Marsan, N, Borodzicz-Jazdzyk, Sonia, Uygur, Beg\ufcm, Uygur, B, Donal, Erwan, Coisne, A, Petersen, Steffen, Velegraki, Eirini, Velegraki, E, Unger, P, Florence, Jeremy, Unger, Alexandre, Petersen, S, Pereira, Christine, Gimelli, Alessia, Bohbot, Y, Muraru, Denisa, Gerber, B, Pontone, G, Ajmone Marsan, Nina, Unger, A, Toupin, Solenn, Dweck, M, Uygur, Begüm, Gimelli, A, Delgado, V, Mandoli, Giulia Elena, Pereira, C, Afana, A, Pezel, T, Bohbot, Yohann, Kagiyama, Nobuyuki, Kagiyama, N, Pezel, Th\ue9o, Pibarot, Philippe, Romero Dorta, E, Florence, J, Donal, E, Clavel, M-A, Unger, Philippe, Gerber, Bernhard, Vicaut, Eric, Delgado, Victoria, Manka, R, Pibarot, P, Neglia, Danilo, Afana, Andreea, Manka, Robert, Pontone, Gianluca, Dweck, Marc   +65 more
core   +1 more source

Heart failure and cardiac imaging : Choosing wisely in the era of multimodality imaging

, 2020
Heart failure is the common final outcome of many heart diseases. Cardiac imaging plays a central role in its diagnosis and etiological work-up. Given the large array of imaging modalities, as well as structural and functional parameters, devising a ...
Flachskampf, Frank, Flachskampf, Frank,, Baron, Tomasz,, Baron, Tomasz   +3 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Clinical update. Computed Tomography — an Emerging Tool for Triple Rule-Out in the Emergency Department. A Review

Journal of Cardiovascular Emergencies, 2017
New imaging tools have been developed in recent years to rapidly and accurately diagnose life-threatening diseases associated with high mortality rates, such as acute coronary syndromes, acute aortic dissection, or pulmonary embolism.
Dobra Mihaela, Bordi Lehel, Nyulas Tiberiu, Stănescu Alexandra, Morariu Mirabela, Condrea Sebastian, Benedek Theodora   +6 more
doaj   +1 more source

Multimodality Imaging [PDF]

Stroke, 2004
Noninvasive “multimodal” in vivo imaging is not just becoming standard practice in the clinic, but is rapidly changing the evolving field of experimental imaging of genetic expression (“molecular imaging”). The development of multimodality methodology based on nuclear medicine (NM), positron emission tomography (PET) imaging, magnetic resonance imaging
Michael Moseley, Geoffrey Donnan
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Pattern recognition systems design on parallel GPU architectures for breast lesions characterisation employing multimodality images [PDF]

, 2014
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University London.The aim of this research was to address the computational complexity in designing multimodality Computer-Aided Diagnosis (CAD) systems for ...
Sidiropoulos, Konstantinos
core