Results 151 to 160 of about 544,818 (296)

Cordycepin mediates neuroprotection against apoptosis via ERK/CREB signaling activation in Aβ1–42‐induced neuronal cell models

Ibrain, Volume 11, Issue 1, Page 84-97, Spring 2025.
This study demonstrates cordycepin's neuroprotective effects against Aβ1–42‐induced apoptosis in neuronal cells, mediated through the activation of the extracellular signal‐regulated kinase/cyclic AMP‐responsive element‐binding protein (ERK/CREB) signaling pathway.
Wenshu Zhou, Cheng Wang, Yige Tan, Philip Lazarovici, Xiaoyan Wen, Shaoping Li, Wenhua Zheng   +6 more
wiley   +1 more source

Design of Ultra Wideband Filter with Double Notch

Guangtongxin yanjiu
【Objective】To enhance the communication quality of Ultra Wideband (UWB) systems and eliminate interference from other narrowband wireless services, a novel UWB filter based on a multimode resonator is proposed.【Methods】Two rejection notches are ...
LI Jun, ZHANG Yang, LIU Jinxian, HE Xiaochun   +3 more
doaj  

New type of multimode-interference-type thermo-optic variable optical attenuator

, 2004
A thermo-optic variable optical attenuator (VOA) based on a Mach-Zehnder interferometer and multimode-interference coupler is fabricated. Not a single-mode but a multimode waveguide is used as the input and output structures of the optical field, which ...
Xin HL, Yang L, Wang, QM, Liu YL, Li F, Li ZM, Fang C, Wang, CX, Yang, L, Chinese Acad Sci, Inst Semicond, State Key Lab Integrated Optoelect, Beijing 100083, Peoples R China. 电子邮箱地址: lyang@red.semi.ac.cn   +8 more
core  

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Pulse Generation through Multimode Interference

Pulsed lasers, particularly ultrashort pulsed lasers, have extensive applications in fields such as spectroscopy, telecommunications, atmospheric measurements, surgery, bio-imaging, and material processing. This chapter explores the use of the single-mode-multimode-single-mode (SMS) structure as an effective means for developing simple, compact, and ...
Sulaiman Wadi Harun, Yu Chen, Ahmad Haziq A. Rosol, Zian Cheak Tiu, Retna Apsari   +4 more
openaire   +1 more source

Multimode-interference-type thermo-optic variable optical attenuator with a response frequency of 10 kHz

, 2003
A thermo-optic variable optical attenuator based on a multimode interference coupler principle is fabricated. The propagation loss of the fabricated device is 1.6 to 3.8 dB at the wavelength range 1510 to 1610 nm, which is very near the calculated value (
Yang L, Liu YL, Wang QM, Wang W, Yang L,Chinese Acad Sci,Inst Semicond,State Key Lab Integrated Optoelect,Beijing 100083,Peoples R China., Cheng Y   +5 more
core  

Cellular Toxicity of Short‐ and Long‐Term Exposures to Polystyrene Nanoplastics and Microplastics in Fish Skin Cell Derived From Fathead Minnow (Pimephales promelas)

Journal of Applied Toxicology, EarlyView.
ABSTRACT The ubiquitous presence of microplastics and nanoplastics (MNPs) is raising concerns about their impact on the health of humans and other living organisms. Due to its tiny size, this particle can accumulate and circulate in the body after uptake, resulting in a variety of harmful outcomes on the organism, such as increased oxidative stress and
Trang Thi Nguyen, Kiyun Park, Ihn‐Sil Kwak   +2 more
wiley   +1 more source

Integrated multimode interference couplers in silicon-on insulator

, 2000
Silicon-on insulator (SOI) is an attractive platform for the fabrication of optoelectronic integrated circuit. Thin cladding layers (m) can be used in SOI waveguide due to the large index step between Si and SiO2, making them compatible with the VLSI ...
Wei HZ, Zhang XF, Liu ZL, Ma HZ, Shi W, Wei HZ Chinese Acad Sci Inst Semicond State Key Lab INtegrated Optoelect Beijing 100083 Peoples R China., Li GH, Fang CS, Yu YZ   +8 more
core  

Controllable DNA Condensation by Mixed Cationic Gemini/Nonionic Surfactant Systems: Structure, Thermodynamics, and Cytotoxicity

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Controllable DNA condensation is important for nucleic‐acid packaging and non‐viral gene‐delivery systems. This study aimed to determine how the composition of mixed nonionic C12E10 and cationic gemini C12C6C12Br2 surfactants regulates DNA condensation, structure, thermodynamics, and cytotoxicity.
Bo Wang, Linyi Zhu, Yaxun Fan, Yilin Wang   +3 more
wiley   +1 more source

Use of predictive tools for the analysis of bioactive compounds in Crocus sativus L. flowers

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Crocus sativus L. (saffron) flowers have high bioactive potential because of their content of crocins, safranal and phenolic compounds. The development of predictive models based on near‐infrared (NIR) spectroscopy and partial least squares regression to estimate the antioxidant capacity of saffron flower, evaluated using oxygen ...
Manuel Piqueras‐García, Jorge F Escobar‐Talavera, María Esther Martínez‐Navarro, Gonzalo L Alonso, Rosario Sánchez‐Gómez   +4 more
wiley   +1 more source