Results 111 to 120 of about 13,119 (253)
Optimizing Oligonucleotide Therapeutics: A Model‐Informed Drug Development Perspective
Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Oligonucleotide therapies have emerged as a powerful therapeutic class, providing novel solutions for diverse diseases through antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), and aptamers that specifically target and modulate gene expression or protein function. However, oligonucleotide development faces distinct challenges,
Ye Yuan +7 more
wiley +1 more source
Journal of Veterinary Pharmacology and Therapeutics, Volume 49, Issue 3, Page 295-305, May 2026.ABSTRACT The pharmacokinetics and pharmacodynamics of betamethasone following intra‐articular administration to horses have been described; however, studies characterizing intramuscular administration are lacking. Twenty‐four horses received an intramuscular dose of 12 mg betamethasone sodium phosphate/betamethasone acetate.
Juliana Sullivan +4 more
wiley +1 more source
Emergency Department: Effectiveness of a Referral Intervention for High Utilizers
, 2014 This research examined the impact of a referral intervention for patients with high utilization of the Emergency Department (ED) for non-‐emergent care.
Kang-Lim, Tina Jee Yung
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A proposed psychological assessment protocol for applicants to religious life in the Roman Catholic Church [PDF]
, 1998 This paper proposes a psychological assessment protocol for applicants to religious life in the Roman Catholic church. While most Catholic religious orders, seminaries, and dioceses require applicants to complete some type of psychological evaluation ...
Boccaccini, Marcus T., Plante, Thomas G.
core +1 more source
New Phytologist, Volume 250, Issue 4, Page 2599-2618, May 2026.Summary Beneficial rhizobacteria and viral pathogens can both alter host plant phenotypes, yet little is known about how their simultaneous presence influences plant metabolism and species interactions. We investigated how two rhizobacteria, Bradyrhizobium japonicum and Delftia acidovorans, together with bean pod mottle virus (BPMV), shape soybean ...
Hannier Pulido +3 more
wiley +1 more source
ChemSusChem, Volume 19, Issue 8, 28 April 2026.Heterogeneous catalysis has historically been developed in the gas phase, however, we have found it pertinent to highlight solvent effects that must be accounted for in liquid environments. Condensed phase catalysis, like that in biomass, petroleum and the conversion of CO2, stands to benefit from the typically overlooked discussion regarding the ...
Jim B. Floyd +3 more
wiley +1 more source
Human Brain Mapping, Volume 47, Issue 6, April 15, 2026.A joint ICA (jICA)‐based “dynamic fusion” framework to identify dynamically tuned SNP manifolds by linking static SNPs to dynamic functional information of the brain. ABSTRACT Many mental disorders show strong genetic influence. In parallel, dynamic functional network connectivity (dFNC) has shown high sensitivity to brain changes related to mental ...
Jiayu Chen +7 more
wiley +1 more source
Robust Inverse Material Design With Physical Guarantees Using the Voigt‐Reuss Net
International Journal for Numerical Methods in Engineering, Volume 127, Issue 7, 15 April 2026.ABSTRACT We apply the Voigt‐Reuss net, a spectrally normalized neural surrogate introduced in [38], for forward and inverse mechanical homogenization with a key guarantee that all predicted effective stiffness tensors satisfy Voigt‐Reuss bounds in the Löwner sense during training, inference, and gradient‐driven optimization.
Sanath Keshav, Felix Fritzen
wiley +1 more source
Alternative Analysis of Different Methods for Estimating Prevalence Rate [PDF]
, 1977 The estimation of disease prevalence is a crucial part of the national planning of health services since it is a necessary step in the calculation of resource requirements.
Shigan, E.N.
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