Results 71 to 80 of about 1,087,603 (247)

Use of cumulative sums for detection of changepoints in the rate parameter of a poisson process [PDF]

, 2004
This paper studies the problem of multiple changepoints in rate parameter of a Poisson process. We propose a binary segmentation algorithm in conjunction with a cumulative sums statistic for detection of changepoints such that in each step we need only ...
Galeano, Pedro
core  

Estimating classification error under edit restrictions in combined survey-register data using Multiple Imputation Latent Class modelling (MILC) [PDF]

, 2016
Both registers and surveys can contain classication errors. These errors can be estimated by making use of information that is obtained when making use of a combined dataset.
Boeschoten, L., Oberski, D.L., de Waal, A.G.   +2 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Assessing paleo channel probability for offshore wind farm ground modeling - comparison of multiple-point statistics and sequential indicator simulation

Applied Computing and Geosciences
The presented study investigates the prediction of buried paleo-channels for probabilistic ground modeling of offshore windfarm development areas using geostatistical methods.
Lennart Siemann, Ramiro Relanez
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The Influence of Geostatistical Prior Modeling on the Solution of DCT-Based Bayesian Inversion: A Case Study from Chicken Creek Catchment

Remote Sensing, 2019
Low frequency loop-loop electromagnetic induction (EMI) is a widely-used geophysical measurement method to rapidly measure in situ the apparent electrical conductivity (ECa) of variably-saturated soils.
Davood Moghadas, Jasper A. Vrugt
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Using multiple-point geostatistics for geomodeling of a vein-type gold deposit

Applied Computing and Geosciences
Geostatistical cascade modeling of Mineral Resources is challenging in vein-type gold deposits. The narrow shape and long-range features of these auriferous veins, coupled with the paucity of drill-hole data, can complicate the modeling process and make ...
Aida Zhexenbayeva, Nasser Madani, Philippe Renard, Julien Straubhaar   +3 more
doaj   +1 more source

Implications of heterogeneity on transport simulations at large scale: the Morroa aquifer case

Revista Facultad de Ingeniería Universidad de Antioquia, 2014
The Morroa aquifer located in Sucre state (northern Colombia) represents the exclusive source of water supply for nearly 500.000 people, including the capital of the state Sincelejo.
Anibal Jose Pérez-García, Oscar García-Cabrejo, Nelson Obregón-Neira   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source