Results 81 to 90 of about 554,448 (293)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Linguistic Picture Fuzzy Dombi Aggregation Operators and Their Application in Multiple Attribute Group Decision Making Problem

Mathematics, 2019
The aims of this study are to propose the linguistic picture fuzzy Dombi (LPFD) aggregation operators and decision-making approach to deal with uncertainties in the form of linguistic picture fuzzy sets.
Muhammad Qiyas, Saleem Abdullah, Shahzaib Ashraf, Lazim Abdullah   +3 more
doaj   +1 more source

An Approach to Multiple Attribute Group Decision Making Based on Intuitionistic Trapezoidal Fuzzy Power Generalized Aggregation Operator [PDF]

International Journal of Computational Intelligence Systems, 2014
With respect to multiple attribute decision making (MADM) problems in which the attribute value takes the form of intuitionistic trapezoidal fuzzy number, a new decision making analysis method is developed.
Peide Liu, Ying Liu
doaj   +1 more source

Generating Competitive Priority Strategy in Transformer Industry [PDF]

, 2018
The transformer market competition in Indonesia is getting more attractive and dynamic. This encourages transformer manufacturers to improve competitiveness, such as quality, cost, timely delivery, and service.
Ambarwati, Rita
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Multi-criteria decision making with linguistic labels: a comparison of two methodologies applied to energy planning [PDF]

, 2014
This paper compares two multi-criteria decision making (MCDM) approaches based on linguistic label assessment. The first approach consists of a modified fuzzy TOPSIS methodology introduced by Kaya and Kahraman in 2011. The second approach, introduced by
Afsordegan, Arayeh, Agell Jané, Núria, Cremades Oliver, Lázaro Vicente, Sánchez Soler, Monica, Zahedi, Siamak   +4 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Multi-test Decision Tree and its Application to Microarray Data Classification [PDF]

, 2014
Objective: The desirable property of tools used to investigate biological data is easy to understand models and predictive decisions. Decision trees are particularly promising in this regard due to their comprehensible nature that resembles the ...
Armstrong, Berzal, Breiman, Breiman, Breiman, Brodley, Brown, Brown, Che, Chen, Cohen, Cordell, Cowell, Czajkowski, Demsar, Dettling, Diaz-Uriarte, Dramiński, Fayyad, Freund, Freund, Ge, Golub, Grześ, Hall, Hastie, Hu, Kuo, Li, Marcin Czajkowski, Marek Grześ, Marek Kretowski, Murthy, Murthy, Pagallo, Qu, Quinlan, Robnik-Siikonja, Rokach, Rokach, Sebastiani, Shalev-Shwartz, Shi, Tan, Tan, Wold, Yeoh   +46 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source