Results 41 to 50 of about 11,261,451 (302)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Conditioning multiple-point statistics simulations to block data [PDF]

Spatial Statistics, 2016
Multiple-points statistics (MPS) allows to generate random fields reproducing spatial statistics derived from a training image. MPS methods consist in borrowing patterns from the training set. Therefore, the simulation domain is assumed to be at the same resolution as the conceptual model, although geometrical deformations can be handled by such ...
Julien Straubhaar, Philippe Renard, Grégoire Mariethoz   +2 more
openaire   +1 more source

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Combining Clustering Methods With MPS to Estimate Structural Uncertainty for Hydrological Models

Frontiers in Earth Science, 2019
This study presents a novel expansion of the clay-fraction (CF)/resistivity clustering method aiming at developing realizations of subsurface structures based on multiple point statistics (MPS).
Troels Norvin Vilhelmsen, Esben Auken, Anders Vest Christiansen, Adrian Sanchez Barfod, Pernille Aabye Marker, Peter Bauer-Gottwein   +5 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

A comparison of multiple-point statistics and two-point statistics for spectral-spatial land cover classification

, 2016
Incorporating spatial information quantified by geostatistical tools to improve the classification of remotely sensed data is a promising method. Most existing studies only focused on the development of geostatistics-based spectral-spatial classification
Peijun Li, Shi, Zhongkui, Zhongkui Shi, Li, Peijun   +3 more
core   +1 more source

Enduring effect of permeability texture for enhancing accuracy and reducing uncertainty of reservoir fluid flow through porous media

Petroleum Science, 2019
Modeling reservoir permeability is one of the crucial tasks in reservoir simulation studies. Traditionally, it is done by kriging-based methods. More rigorous modeling of the permeability results in more reliable outputs of the reservoir models. Recently,
Arash Azamifard, Fariborz Rashidi, Mohammadreza Pourfard, Mohammad Ahmadi, Bahram Dabir   +4 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

A fast 3D reconstruction algorithm of multiple point statistics

四川大学学报. 自然科学版, 2016
Based on the SNESIM algorithm, a fast three-dimensional(3D) reconstruction algorithm of multiple-point statistics simulation was proposed. First, pattern sets were built by the red-black tree. The height of tree structures was rapidly reduced.
ZUO Chen, TENG Qi-Zhi, HE Xiao-Hai, GAO Ming-Liang   +3 more
doaj