Results 91 to 100 of about 20,794,413 (306)
Nonlinear Torsional Vibration of Size-Dependent Functionally Graded Rods [PDF]
Mechanics of Advanced Composite StructuresThis study aims to investigate the effect of functionally graded materials (FGMs) on the internal resonances of nanorods in torsional vibration. The von-Kármán type nonlinearity is considered and the governing equation of motion is derived using Hamilton'
Reza Nazemnezhad +2 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Construct validity, dimensionality and factorial invariance of the Rosenberg Self Esteem Scale: A bifactor modelling approach among children of prisoners [PDF]
, 2014 The Rosenberg Self Esteem Scale (RSES; Rosenberg, 1989) has traditionally been conceptualised as a unidimensional measure of self-esteem but empirical evidence is equivocal, with some studies supporting a one-factor solution and others favouring ...
Daniel Boduszek +7 more
core +1 more source
Scientific ReportsIncreasing the span length of stay cables markedly increases their susceptibility to parametric resonance. This study investigates mitigating parametric resonance in stay cables using a parallel inerter damper and focuses on a methodology to obtain the ...
Zengwei Guo +3 more
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
The Scientific World Journal, 2015 Multiscale nondestructive characterization of coal microscopic physical structure can provide important information for coal conversion and coal-bed methane extraction.
Haipeng Wang +5 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source