The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Fast-Decodable Space–Time Codes for the -Relay and Multiple-Access MIMO Channel [PDF]
, 2015 Amaro Barreal +2 more
openalex +1 more source
Joint effects of prenatal household air pollution exposure from multiple sources on preterm birth - A case-control study with propensity score matching [PDF]
, 2022 Xin-Chen Liu +9 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A Case of Multiple Myeloma: Mimicking Carcinoma Larynx [PDF]
, 2016 Santhosh Kumar Nochikattil +4 more
openalex +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Comparative Cost Utility Analysis of Plerixafor Plus GCSF Versus Cyclophosphamide Plus GCSF as Salvage Mobilization Regimens in Multiple Myeloma Patients [PDF]
, 2012 Haitham Tuffaha +2 more
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Supplementary Figure 4 from Multiple Alternative Splicing Markers for Ovarian Cancer [PDF]
, 2023 Roscoe Klinck +14 more
openalex +1 more source