Results 81 to 90 of about 18,779,242 (350)
The risks of multiple breadbasket failures in the 21st century: a science research agenda [PDF]
, 2017 Thomson ReutersThis report stems from an international, interdisciplinary workshop organized by Knowledge Systems for Sustainability and hosted by the Frederick S. Pardee Center for the Study of the Longer-Range Future, with support from Thomson Reuters,
Glauber, Joseph +5 more
core +1 more source
Multiple Target, Multiple Type Filtering in the RFS Framework
, 2019 A Multiple Target, Multiple Type Filtering (MTMTF) algorithm is developed using Random Finite Set (RFS) theory. First, we extend the standard Probability Hypothesis Density (PHD) filter for multiple types of targets, each with distinct detection ...
Baisa, Nathanael L., Wallace, Andrew
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Preoperative computed tomography-guided soft hook-wire localization for multiple pulmonary nodules
Frontiers in OncologyBackgroundWhile there have been prior reports on pulmonary nodule (PN) localization through computed tomography (CT)-guided soft hook-wire (SHW) placement, there remains a dearth of studies specifically focused on the CT-guided SHW localization of ...
Guang-Chao Li +4 more
doaj +1 more source
Dimethyl Fumarate Treatment Reduces the Amount but Not the Avidity of the Epstein–Barr Virus Capsid-Antigen-Specific Antibody Response in Multiple Sclerosis: A Pilot Study [PDF]
, 2023 Massimiliano Castellazzi +7 more
openalex +1 more source
Pure Exploration with Multiple Correct Answers [PDF]
, 2019 We determine the sample complexity of pure exploration bandit problems with multiple good answers. We derive a lower bound using a new game equilibrium argument.
Degenne, Rémy, Koolen, Wouter M.
core +1 more source
Multiple targets for multiple sclerosis
Genes & Diseases, 2015 Multiple sclerosis (MS), a leading cause of non-traumatic disability in young adults, is a chronic inflammatory demyelinating disease of the central nervous system (CNS) associated with aberrant autoimmune responses. It has long been thought that therapeutic development should be centered on immunomodulatory agents.
Hu, Li-Tian, Sun, Fei, Chen, Guo-Jun
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The mechanism of multiple organ dysfunction syndrome in patients with COVID‐19
, 2022 Wenbin Zhao +4 more
openalex +2 more sources
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source