Results 1 to 10 of about 7,742,036 (343)

Chromosome 1q21 abnormalities in multiple myeloma [PDF]

Blood Cancer Journal, 2021
Gain of chromosome 1q (+1q) is one of the most common recurrent cytogenetic abnormalities in multiple myeloma (MM), occurring in approximately 40% of newly diagnosed cases.
Timothy M. Schmidt, Rafael Fonseca, Saad Z. Usmani   +2 more
doaj   +4 more sources

Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice. [PDF]

Sci Rep, 2016
DGCR8 is an RNA-binding protein that interacts with DROSHA to produce pre-microRNA in the nucleus, while DICER generates not only mature microRNA, but also endogenous small interfering RNAs in the cytoplasm.
Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H.   +12 more
europepmc   +2 more sources

A deep-learning-based framework for identifying and localizing multiple abnormalities and assessing cardiomegaly in chest X-ray. [PDF]

Nat Commun
Accurate identification and localization of multiple abnormalities are crucial steps in the interpretation of chest X-rays (CXRs); however, the lack of a large CXR dataset with bounding boxes severely constrains accurate localization research based on ...
Fan W, Yang Y, Qi J, Zhang Q, Liao C, Wen L, Wang S, Wang G, Xia Y, Wu Q, Fan X, Chen X, He M, Xiao J, Yang L, Liu Y, Chen J, Wang B, Zhang L, Yang L, Gan H, Zhang S, Liu G, Ge X, Cai Y, Zhao G, Zhang X, Xie M, Xu H, Zhang Y, Chen J, Li J, Han S, Mu K, Xiao S, Xiong T, Nian Y, Zhang D.   +37 more
europepmc   +2 more sources

Genetic Abnormalities in Multiple Myeloma: Prognostic and Therapeutic Implications

Cells, 2021
Some genetic abnormalities of multiple myeloma (MM) detected more than two decades ago remain major prognostic factors. In recent years, the introduction of cutting-edge genomic methodologies has enabled the extensive deciphering of genomic events in MM.
Ignacio J. Cardona-Benavides, Cristina de Ramón, Norma C. Gutiérrez   +2 more
doaj   +2 more sources

Congenital Abnormalities and Multiple Sclerosis [PDF]

BMC Neurology, 2010
Background There is a strong maternal parent-of-origin effect in determining susceptibility to multiple sclerosis (MS). One hypothesis is that an abnormal intrauterine milieu leading to impaired fetal development could plausibly also result in increased ...
Orton Sarah-Michelle, Dyment David A, Criscuoli Maria, Guimond Colleen, Ramagopalan Sreeram V, Yee Irene M, Ebers George C, Sadovnick Dessa   +7 more
doaj   +4 more sources

Multiple Congenital Heart Abnormalities [PDF]

Acta Medica Bulgarica, 2019
Congenital heart abnormalities are rare and most often occur separately. These structural and functional disorders can cause a range of diseases that vary in severity, from mild or even asymptomatic to severe and life-threatening.
Lazarov S., Bogdanov G., Nikolov R.
doaj   +2 more sources

Sleep Abnormalities in Multiple Sclerosis [PDF]

Current Treatment Options in Neurology, 2019
This review summarizes the most well-documented sleep disorders seen in patients with multiple sclerosis (MS), with a special focus on the impact on quality of life.Sleep abnormalities in patients with MS are a multifactorial and relatively complex issue affecting approximately 60% of the patients while the pathophysiology of these symptoms is not ...
Sakkas, Giorgos K., Giannaki, Christoforos D., Karatzaferi, Christina, Manconi, Mauro   +3 more
openaire   +5 more sources

Chromosomal Abnormalities in Multiple Myeloma [PDF]

Blood, 1967
Abstract Chromosome studies were carried out in five cases of multiple myeloma by peripheral leukocyte culture and direct preparation from bonemarrow cells. No chromosomal abnormality was detected by leukocyte culture in any of these cases.
K C, Das, B K, Aikat
openaire   +3 more sources

Systemic multiple myeloma and colonic abnormalities

VideoGIE, 2023
Video 1Colonic abnormalities observed in the course of systemic multiple myeloma.
Katarzyna M. Pawlak, MD, PhD, MRCPUK, Kareem Khalaf, MD, Klaus Mönkemüller, MD, PhD, FJGES, Krzysztof Kurek, MD, PhD   +3 more
doaj   +3 more sources

Comparison of Intraspinal Abnormalities Prevalence in Congenital Scoliosis [PDF]

JBJS Open Access
Background:. The increasing utilization of magnetic resonance imaging has facilitated the detection of intraspinal abnormalities in congenital scoliosis (CS) caused by hemivertebra.
Li Jie, MD, PhD, Chen Chunxiao, MS, Qin Xiaodong, MD, PhD, Hu Zongshan, MD, PhD, Qiao Jun, MD, PhD, Mao Saihu, MD, PhD, Shi Benlong, MD, PhD, Qiu Yong, MD, PhD, Zhu Zezhang, MD, PhD, Liu Zhen, MD, PhD   +9 more
doaj   +2 more sources