Results 91 to 100 of about 1,089,170 (344)
Possible role of human ribonuclease dicer in the regulation of R loops
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik+2 more
wiley +1 more source
Experience of the diagnosis and observation of a child with wolf-hirschhorn syndrome
Modern data about the causes, course peculiarities, principles of diagnosis and symptomatic treatment of Wolf-Hirshhorn syndrome are given in the article. The description of own clinical case is presented.
L.V. Besh+5 more
doaj +1 more source
The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji+3 more
wiley +1 more source
When Alcoholism Affects Memory Functions: MRI of the Brain. [PDF]
The development of modern imaging techniques makes it possible to examine directly the relationship between brain abnormalities and memory impairment.
Jernigan, Terry L, Ostergaard, Arne L
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Flower-Like Plasma Cell Nuclei in Multiple Myeloma
Abibatou Sall+6 more
doaj +1 more source
Cytogenetic and FISH analysis of 93 multiple myeloma Moroccan patients
Background Multiple myeloma (MM) is a disease characterized by heterogeneous clinical presentations as well as complex genetic and molecular abnormalities.
Hasna Hamdaoui+9 more
doaj +1 more source
The role of circular RNAs in regulating cytokine signaling in cancer
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi+4 more
wiley +1 more source
Abnormalities in Brain Esterases in Multiple Sclerosis.
SummaryVertical starch-gel electrophoresis has been used for preparation of esterase zymograms of postmortem specimens of human brain. The specimens derived from 36 cases without a history of significant neurologic disability and 13 cases of multiple sclerosis.
Kevin D. Barron+2 more
openaire +3 more sources
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki+11 more
wiley +1 more source
Deep learning-based parameter mapping for joint relaxation and diffusion tensor MR Fingerprinting
Magnetic Resonance Fingerprinting (MRF) enables the simultaneous quantification of multiple properties of biological tissues. It relies on a pseudo-random acquisition and the matching of acquired signal evolutions to a precomputed dictionary.
Buonincontri, Guido+15 more
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