Results 171 to 180 of about 1,089,170 (344)

PROGNOSTIC IMPACT OF CYTOGENETIC ABNORMALITIES AND R2-ISS IN MULTIPLE MYELOMA

Hematology, Transfusion and Cell Therapy
Introduction: Cytogenetic abnormalities are crucial for risk stratification and therapeutic decisions in multiple myeloma (MM). The incorporation of 1q+ into the R2-ISS prognostic tool has revealed a new subgroup of very high-risk patients not previously
LS Abreu, ML Puls, RAF Machado, TFN Araújo, CD Liz, PHA Moraes, RS Szor, EL Rosa, VC Molla, CA Rodrigues   +9 more
doaj  

Axonal loss results in spinal cord atrophy, electrophysiological abnormalities and neurological deficits following demyelination in a chronic inflammatory model of multiple sclerosis [PDF]

, 2000
Dorian B. McGavern
openalex   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

Human Lymphocyte-Specific Protein 1, the Protein Overexpressed in Neutrophil Actin Dysfunction with 47-kDa and 89-kDa Protein Abnormalities (NAD 47/89), Has Multiple F-Actin Binding Domains [PDF]

, 2000
Qihong Zhang, Yao Li, Thomas H. Howard
openalex   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Metabolic abnormalities in multiple symmetric lipomatosis: elevated lipoprotein lipase activity in adipose tissue with hyperalphalipoproteinemia.

, 1983
Giuliano Enzi, Laura Favaretto, S. Martini, R. Fellin, Aldo Baritussio, Giovanni Gambaro, Gaetano Crepaldi   +6 more
openalex   +1 more source

Microstructural and Mechanical Properties of a Hard Anodic Coating Applied on an Elastically Prestrained Aluminum Substrate

Advanced Engineering Materials, EarlyView.
Prestraining the substrate influences coating formation process. Higher prestraining force leads to higher coating thickness and lower hardness. Increase in prestraining force enhances preliminary damage in hard anodic coating. Fatigue damage mechanisms change for hard anodized prestrained samples.
Linto George Thomas, Lisa Winter, Frank Simchen, Tobias Breitfeld, Thomas Lampke   +4 more
wiley   +1 more source

A deep-learning-based framework for identifying and localizing multiple abnormalities and assessing cardiomegaly in chest X-ray. [PDF]

Nat Commun
Fan W, Yang Y, Qi J, Zhang Q, Liao C, Wen L, Wang S, Wang G, Xia Y, Wu Q, Fan X, Chen X, He M, Xiao J, Yang L, Liu Y, Chen J, Wang B, Zhang L, Yang L, Gan H, Zhang S, Liu G, Ge X, Cai Y, Zhao G, Zhang X, Xie M, Xu H, Zhang Y, Chen J, Li J, Han S, Mu K, Xiao S, Xiong T, Nian Y, Zhang D.   +37 more
europepmc   +1 more source

Joule‐Assisted Nanotherapeutic Urethral Stent (JANUS) for Spatiotemporal Theragenerative Treatment of Urethral Strictures

Advanced Functional Materials, EarlyView.
Joule‐assisted nanotherapeutic urethral stent harnesses a smart, biodegradable magnesium stent to orchestrate spatiotemporal theragenerative therapy for urethral strictures. Magnetically induced Joule heating enables on‐demand drug release and bacterial ablation, while simultaneously guiding urothelial regeneration.
Yuhyun Na, Yubeen Park, Hyun Lee, Song Hee Kim, Seojoon Bang, Hyeong Seok Kang, Chan Ho Moon, Ju Yeong Gwon, Jong Hwa Seo, Min‐Ho Kang, Soo‐Hong Lee, Gi Doo Cha, Wooram Park, Heemin Kang, Jung‐Hoon Park, Hyun‐Do Jung   +15 more
wiley   +1 more source

Incidence of CSF abnormalities in siblings of multiple sclerosis patients and unrelated controls [PDF]

, 2000
Sara Haghighi, Oluf Andersen, Lars Rosengren, Tomas Bergström, Jan Wahlström, Staffan Nilsson   +5 more
openalex   +1 more source