Results 81 to 90 of about 1,089,170 (344)

The effects of hemodynamic lag on functional connectivity and behavior after stroke [PDF]

, 2015
Stroke disrupts the brain's vascular supply, not only within but also outside areas of infarction. We investigated temporal delays (lag) in resting state functional magnetic resonance imaging signals in 130 stroke patients scanned two weeks, three months
Corbetta, Maurizio, Ramsey, Lenny, Shulman, Gordon L, Siegel, Joshua S, Snyder, Abraham Z   +4 more
core   +1 more source

CSF Abnormalities in Earlier- and Later-Onset Pediatric Multiple Sclerosis Compared

Pediatric Neurology Briefs, 2010
CSF cellular and immunoglobulin G (IgG) profiles in 40 earlier-onset (11 and
J Gordon Millichap
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Detail-oriented cognitive style and social communicative deficits, within and beyond the autism spectrum: independent traits that grow into developmental interdependence [PDF]

, 2013
At the heart of debates over underlying causes of autism is the "Kanner hypothesis" that autistic deficits in social reciprocity, and a cognitive/perceptual 'style' favouring detail-oriented cognition, co-vary in autistic individuals.
Austin, Baranek, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Baron-Cohen, Belmonte, Belmonte, Belmonte, Belmonte, Belmonte, Ben-Sasson, Benton, Best, Beuker, Bishop, Boomsma, Boyd, Boyd, Carroll, Charman, Charman, Chen, Chen, Constantino, Cuccaro, Dawson, Dworzynski, Eisenberg, Evans, Evers, Frazier, Frazier, Frith, Georgiades, Georgiades, Geschwind, Golan, Gotham, Gotham, Grove, Happé, Happé, Happé, Hoekstra, Honey, Hurst, Jarrold, Jeffrey M. Valla, Johnson, Johnson, Kamp-Becker, Kanner, Kern, Kloosterman, Kolevzon, Lam, Lau, Lord, Magyer, Mandy, Mandy, Matson, Matthew K. Belmonte, McGovern, Morgan, Ozonoff, Papageorgiou, Pellicano, Pellicano, Piven, Richler, Rogers, Ronald, Ronald, Rubenstein, Russell-Smith, Sacco, Silverman, Skuse, Smith, Snow, Spiker, Stewart, Szatmari, Szatmari, Tadevosyan-Leyfer, Trope, Turner, Valla, Van Lang, Voracek, Walter, Watson, Wimmer, Witelson, Witkin, Yoder   +105 more
core   +1 more source

Evaluation of CD56 and CD117 Double-Positivity as a Predictor of Poor Prognosis in Multiple Myeloma Patients: A Retrospective Analysis

Turkish Journal of Hematology
Objective: Despite advancements in treatment, multiple myeloma (MM) remains a challenging hematologic malignancy. It is crucial to stratify risk and perform prognostic assessment with various markers, including the expression of cluster of ...
Hakan Keski, Selim Merdan, Itır Ebru Zemheri   +2 more
doaj   +1 more source

Prenatal diagnosis and genetic analysis of fetal akinesia deformation sequence and multiple pterygium syndrome associated with neuromuscular junction disorders: A review

Taiwanese Journal of Obstetrics & Gynecology, 2012
Fetal akinesia deformation sequence is a clinically and genetically heterogeneous disorder characterized by a variable combination of arthrogryposis, fetal akinesia, intrauterine growth restriction, developmental abnormalities such as cystic hygroma ...
Chih-Ping Chen
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

A Case Report of Marfan Syndrome with Literature Review [PDF]

, 2015
Marfan syndrome(MFS) is a connective tissue disorder that affects multiple organ systems. Cardiovascular, ocular, and skeletal abnormalities are cardinal features of the syndrome. Its incidence is among the highest of any heritable disorder.Most patients
Kalla, H. K. (Hemanth), kumari, S. (Swarna), parthasarathy, M. (MKR), rao, C. R. (CH), reddy, S. S. (S), Revathi, M. (M)   +5 more
core  

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source