Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Adaptive Channel Division and Subchannel Allocation for Orthogonal Frequency Division Multiple Access-Based Airborne Power Line Communication Networks. [PDF]
Yan R, Li Q, Xiong H.
europepmc +1 more source
From Constellation Dithering to NOMA Multiple Access: Security in Wireless Systems. [PDF]
Grzesiak K, Piotrowski Z.
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Intelligent Omni-Surface-Assisted Cooperative Hybrid Non-Orthogonal Multiple Access: Enhancing Spectral Efficiency Under Imperfect Successive Interference Cancellation and Hardware Distortions. [PDF]
John Kennedy HS, Kumaravelu VB.
europepmc +1 more source
Dynamic Divide Grouping Non-Orthogonal Multiple Access in Terrestrial-Satellite Integrated Network. [PDF]
Yan Y, Xu H, Zhang N, Han G, Liu M.
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Age of Information Analysis for Multi-Priority Queue and Non-Orthoganal Multiple Access (NOMA)-Enabled Cellular Vehicle-to-Everything in Internet of Vehicles. [PDF]
Zhang Z, Wu Q, Fan P, Fan Q.
europepmc +1 more source
DFT-Spread Spectrally Overlapped Hybrid OFDM-Digital Filter Multiple Access IMDD PONs. [PDF]
Sankoh A +6 more
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source

