Results 71 to 80 of about 229,527 (307)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Performance improvement of non-orthogonal multiple access scheme using code division multiplexing

open access: yesInternational Journal of Distributed Sensor Networks, 2017
Currently, the standardization of fifth-generation mobile communication system (5G), which realizes 10 Gbps transmission, is in progress. In mobile communications, it is generally difficult to perform high-capacity transmission because of channel fading.
Hiroki Kitagawa, Eiji Okamoto
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Channel Estimation in Uplink SCMA System

open access: yesИзвестия высших учебных заведений России: Радиоэлектроника, 2016
The effect of channel estimation error on bit error probability of uncoded and coded sparse code multiple access (SCMA) system in uplink channel with block fading is considered.
A. B. Sergienko, V. P. Klimentjev
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Classical -Quantum Multiple Access Channel with Secrecy Constraint: One-shot Rate Region

open access: yesInternational Journal of Information and Communication Technology Research, 2020
In this paper, we aim to study a -user quantum multiple access wiretap channel with an arbitrary number of wiretappers under one-shot setting. In this regard, we first introduce the general quantum multiple access wiretap channel and the simplified ...
Hadi Aghaee, Bahareh Akhbari
doaj  

Multi-Class Cost-Constrained Random Coding for Correlated Sources over the Multiple-Access Channel. [PDF]

open access: yesEntropy (Basel), 2021
Rezazadeh A   +3 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

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