Results 71 to 80 of about 437,781 (261)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Analysis of Outage Capacity of NOMA: SIC vs. JD
Tsinghua Science and Technology, 2016 In fifth-generation wireless communication networks, Non-Orthogonal Multiple Access (NOMA) has attracted much attention in both academic and industrial fields because of its higher spectral efficiency in comparison with orthogonal multiple access ...
Shuang Chen +3 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Channel Estimation in Uplink SCMA System
Известия высших учебных заведений России: Радиоэлектроника, 2016 The effect of channel estimation error on bit error probability of uncoded and coded sparse code multiple access (SCMA) system in uplink channel with block fading is considered.
A. B. Sergienko, V. P. Klimentjev
doaj
A Capacity-Achieving Feedback Scheme of the Gaussian Multiple-Access Channel with Degraded Message Sets. [PDF]
Entropy (Basel), 2021 Yuan H, Dai B.
europepmc +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
EURASIP Journal on Wireless Communications and Networking, 2018 Space-division multiple access (SDMA) utilizes linear precoding to separate users in the spatial domain and relies on fully treating any residual multi-user interference as noise. Non-orthogonal multiple access (NOMA) uses linearly precoded superposition
Yijie Mao, Bruno Clerckx, Victor O.K. Li
doaj +1 more source