Results 161 to 170 of about 494,961 (258)

Plant viral suppressors HcPro and P19 inhibit CRISPR-Cas13-mediated transcript interference. [PDF]

Stress Biol
Sharma VK, Marla S, Cook DE.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Applying an intersectional framework to characterize chronic pain disparities one year following traumatic spinal cord injury. [PDF]

J Pain
Fundaun J, Falasinnu T, Pfyffer D, Dildine TC, Kolski M, Heinemann AW, Tharin S, Smith AC, Dirlikov B, Mackey S, Crew J, Weber KA.   +11 more
europepmc   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Differences in retroactive interference response reveal sex-specific memory resilience in pre-symptomatic triple transgenic Alzheimer's disease mice. [PDF]

Brain Commun
D'Amelio C, Autelitano S, Natale F, Rinaudo M, Fusco S, Grassi C.   +5 more
europepmc   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Empowered Relief vs Cognitive Behavioral Therapy for Patients With Systemic Lupus Erythematosus and Chronic Pain: Study Protocol for a National, Randomized, Noninferiority Trial. [PDF]

JMIR Res Protoc
Falasinnu T, Hailu AY, Monson EA, Clifton J, Torres C, Dildine TC, Dorsonne B, Heggan E, Riazi G, Slater K, Poupore-King H, Perez L, Hellewell J, Tian L, Denton S, DeVries A, Miefert J, Mackey SC, Cheung M, Darnall BD.   +19 more
europepmc   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Latent Profiles of Problematic Short-Video Use and Presenteeism Among Hospital Nurses: The Mediating Role of Work Interference With Personal Life. [PDF]

Nurs Open
Liu Z, Li M, Liu Y, Yang P, Liu W, Hu B.
europepmc   +1 more source