Results 91 to 100 of about 618,533 (343)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
A supplier selection using a hybrid grey based hierarchical clustering and artificial bee colony [PDF]
, 2014 Selection of one or a combination of the most suitable potential providers and outsourcing problem is the most important strategies in logistics and supply chain management. In this paper, selection of an optimal combination of suppliers in inventory and
Farshad Faezy Razi
core +1 more source
Correction to: Multiple attribute group decision-making based on generalized aggregation operators under linguistic interval-valued Pythagorean fuzzy environment [PDF]
, 2021 Rajkumar Verma, Nikunj Agarwal
openalex +1 more source
Dual hesitant pythagorean fuzzy Hamacher aggregation operators in multiple attribute decision making
Archives of Control Sciences, 2017 In this paper, we investigate the multiple attribute decision making (MADM) problem based on the Hamacher aggregation operators with dual Pythagorean hesitant fuzzy information.
Wei Guiwu, Lu Mao
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Group consensus measurement in MADM with multiple preference formats [PDF]
An approach is proposed for measuring the group consensus in multiple attribute decision-making (MADM) problems with experts’ various preference information on alternatives.
Xu, Z, Zhang, Q, Zhou, B
core +1 more source
Dombi Aggregation Operators of Linguistic Cubic Variables for Multiple Attribute Decision Making
Information, 2018 A linguistic cubic variable (LCV) is comprised of interval linguistic variable and single-valued linguistic variable. An LCV contains decision-makers’ uncertain and certain linguistic judgments simultaneously.
Xueping Lu, Jun Ye
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
An enhanced intelligent database engine by neural network and data mining [PDF]
, 2000 An Intelligent Database Engine (IDE) is developed to solve any classification problem by providing two integrated features: decision-making by a backpropagation (BP) neural network (NN) and decision support by Apriori, a data mining (DM) algorithm ...
Chua, Boon Lay +2 more
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source