Results 111 to 120 of about 554,506 (291)

Dynamic Multi-Attribute Group Decision Making Model Based on Generalized Interval-Valued Trapezoidal Fuzzy Numbers

open access: yesCybernetics and Information Technologies, 2015
In this paper we investigate the dynamic multi-attribute group decision making problems, in which all the attribute values are provided by multiple decision makers at different periods. In order to increase the level of overall satisfaction for the final
Lin Wei, Yan Guangle, Shi Yuwen
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Does the National Institute for Health and Clinical Excellence take account of factors such as uncertainty and equity as well as incremental cost-effectiveness in commissioning health care services? A binary choice experiment [PDF]

open access: yes
Background: NICE is an independent organisation responsible for providing national guidance on the promotion of good health and the prevention and treatment of ill health in England and Wales. One of NICE’s main roles is to produce national guidance on
Brazier, J.   +2 more
core   +3 more sources

Verifying Credence Attributes in Livestock Production [PDF]

open access: yes
Livestock producers can respond to increasing consumer demand for certain production process attributes by providing verifiable information on the practices used.
Olynk, Nicole J.   +2 more
core   +1 more source

Fuzzy prioritized operators and their application to multiple attribute group decision making

open access: yesApplied Mathematical Modelling, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Zhao, Xiaofei, Lin, Rui, Wei, Guiwu
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Can models be useful for deciding to convert to organic fruit growing ? An introduction to the discussion [PDF]

open access: yes, 2008
Modern high-input agriculture has produced great increases in crop yields but social and environmental costs have also been high. Over the past decades, sustainability has become more and more a guiding principle in agriculture.
Warlop, F.
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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