Results 71 to 80 of about 18,010,905 (289)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Resistance to medical artificial intelligence is an attribute in a compensatory decision process: response to Pezzo and Becksted (2020) [PDF]
, 2020 In Longoni et al. (2019), we examine how algorithm aversion influences utilization of healthcare delivered by human and artificial intelligence providers.
Bonezzi, Andrea +2 more
core +1 more source
Modelling and optimizing multiple attribute decisions by using fuzzy sets [PDF]
The purpose of this paper is to present a coherent perspective of modeling and optimizing multiple attribute decisions by using fuzzy sets. In management practice we face most of the time the situation in which a problem have several possible solutions ...
Adina NEGRUSA, Gh. Gh. IONESCU
core
As an enhanced version of traditional linguistic term sets, Probabilistic Linguistic Term Sets (PLTS) incorporate probabilistic information, thereby offering a more robust approach to Multiple Attribute Group Decision-Making (MAGDM) and significantly ...
Xin Liang, Weijia Kang, Yan Peng
core +1 more source
, 2020 The probabilistic dual hesitant fuzzy sets (PDHFSs), which are able to consider multiple membership and non-membership degrees as well as their probabilistic information, provide decision experts a flexible manner to evaluate attribute values in ...
Jun Wang, Hegong Lei, Li Li
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Information, 2017 Linguistic neutrosophic numbers (LNN) is presented by Fang and Ye in 2017, which can describe the truth, falsity, and indeterminacy linguistic information independently.
Changxing Fan, Jun Ye, Keli Hu, En Fan
doaj +1 more source
Multiple criteria decision making
, 1973 817 p., fig., ref. bib. : 17 p.1/2This volume is the direct result of a seminar on Multiple Criteria Decision Making held at the University of South Carolina on October 26-27, 1972. Support for this seminar and for production of this book was provided by
ZELENY, Milan, COCHRANE, James L.
core
Critical review of multi-criteria decision aid methods in conceptual design phases: application to the development of a solar collector structure [PDF]
, 2014 At each stage of the product development process, the designers are facing an important task which consists of decision making. Two cases are observed: the problem of concept selection in conceptual design phases and, the problem of pre-dimensioning once
EL AMINE, Mehdi +3 more
core +1 more source