Results 181 to 190 of about 106,754 (306)

Patient‐Derived 3D‐Bioprinted Intrahepatic Cholangiocarcinoma Models Recapitulate Tumor Autologous Traits and Predict Personalized Adjuvant Therapy

Advanced Science, EarlyView.
Leveraging 3D bioprinting, this study establishes patient‐derived in vitro models of intrahepatic cholangiocarcinoma. These models faithfully recapitulate the histopathology, molecular profiles, and genomic characteristics of the original patient tumors.
Yuce Lu, Liwei Du, Minghao Sun, Kai Zhang, Mingchang Pang, Shangze Jiang, Jiaxun Dong, Xiyue Liu, Bao Jin, Fu Xu, Hang Sun, Jiangang Zhang, Huiyu Yang, Xiaobo Yang, Xin Lu, Yiyao Xu, Haitao Zhao, Shunda Du, Xinting Sang, Yongchang Zheng, Lei Zhang, Xueshuai Wan, Huayu Yang, Yilei Mao   +23 more
wiley   +1 more source

Searching for a Connection Between the Phenomenon of Transport Exclusion and the Presence of Gastroenterological Symptoms: A Survey of Secondary School Students in Poland. [PDF]

Nutrients
Szyller HP, Mytych A, Augustynowicz G, Dziedziak M, Lasocka M, Michałek M, Pytrus T.   +6 more
europepmc   +1 more source

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

Exploring how economic level drives urban flood risk. [PDF]

Nat Commun
Fan J, Liu B, Lei T, Sun Y, Ma Y, Guo R, Chen D, Zhou K, Li S, Gao X.   +9 more
europepmc   +1 more source

ALKBH3 m1A Demethylase Deficiency Reduces Alzheimer's Amyloid‐β Pathology

Advanced Science, EarlyView.
This study identifies that ALKBH3‐driven m1A demethylation orchestrates Alzheimer's disease progression by disrupting mitochondrial and synaptic homeostasis. This epitranscriptomic mechanism suppresses PINK1‐mediated mitophagy via m1A erasure, leading to mitochondrial dysfunction, oxidative stress, elevated Aβ production, and impaired microglial ...
Yueyang Li, Sifei Yu, Kaidong Lu, Yujie Zhang, Mingjie Dong, Yan Peng, Liang Xue, Waleed Alam, Yuxuan Shui, Yi Zhou, Wuyunhan Ma, Meng Bao, Peiming Li, Peiyi Luo, Tiezhan Lu, Jiajia Li, Kang Zhang, Yuying Wang, Shuchen Yang, Nuoya Yin, Francesco Faiola, Zilong Gao, Jingfeng Zhou, Fei Zhao, Yali He, Magdalena J. Koziol   +25 more
wiley   +1 more source

Predictive estimations of health systems resilience using machine learning. [PDF]

BMC Med Inform Decis Mak
Jatobá A, de Castro-Nunes P, Palmieri P, Machado Araujo de Oliveira O, Passos Simões P, da Silva Fonseca V, de Carvalho PVR.   +6 more
europepmc   +1 more source

Boosting Fast‐Charging Performance of Ni‐Rich NCM9055 Cathodes with Nb2O5 Dual Functional Modification

Advanced Science, EarlyView.
A dual‐functional Nb2O5 modulation strategy is reported to overcome kinetic limitations in Ni‐rich cathodes. The formation of LiNbO3 phase at the grain boundary of the polycrystalline NCM9055 cathode preserves a radially aligned microstructure and establishes fast lithium‐ion pathways.
Tian Rao, Zhaowen Bai, Jian Wang, Yang Ren, Qingsong Weng, Zhongzhu Liu, Maxim Avdeev, Robson Monteiro, Luanna Parreira, Xuejie Huang, Guohua Chen, Yongming Zhu   +11 more
wiley   +1 more source

Childhood Asthma and Community Resilience. [PDF]

Pediatr Pulmonol
Lichtveld MY, Heimke KK, Dietz LJ, Wahid FA, Buchanich JM, Earle BC, Noah TL.   +6 more
europepmc   +1 more source

Photo‐Responsive Room‐Temperature Phosphorescent Films Exhibiting Photochromism and Time‐Dependent Phosphorescent Colors for Multilevel Anti‐Counterfeiting

Advanced Science, EarlyView.
A series of photo‐responsive polymers are prepared by a facile one‐pot in situ synthesis strategy, where RTP modules and photochromic units are systematically integrated into one polymer system. The triplet‐singlet Förster resonance energy transfer (TS‐FRET) between the donor and acceptor enables the material to exhibit time‐dependent phosphorescence ...
Ziyi Bai, Xinyi Xu, Jinbo Fu, Di Zhao, Yige Wang, Huanrong Li   +5 more
wiley   +1 more source

Springer Open Access Publication Current Environmental Health Report Social Equity in True Cost Accounting of Food. [PDF]

Curr Environ Health Rep
Scialabba NE, Merrigan K, Obst C, Riemer O, Jeangros L, Mueller A.   +5 more
europepmc   +1 more source