Results 121 to 130 of about 7,430,828 (301)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Investigation of multiple spindle characteristics under non-uniform bearing preload
Advances in Mechanical Engineering, 2016 The non-uniform distribution load during machining and assembly process is crucial for spindle system, especially in complex working conditions. The conception of non-uniform preload adjustment approach was proposed and experimentally investigated in ...
Yanfei Zhang +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Приборы и методы измерений, 2015 Metrological features of photovoltaic semiconductor converters (PSC) based on semiconductors with the multiple-charge impurities are investigated in a wide range of power densities of optical radiation.
O. K. Gusev +3 more
doaj
RELATING FARM AND OPERATOR CHARACTERISTICS TO MULTIPLE GOALS [PDF]
Farm Management,
Claypool, P.L. +3 more
core +1 more source
Community space in complex learning communities : lessons learnt [PDF]
, 2006 Highly complex learning communities where diverse participants collaborate to achieve multiple aims through synergy have the potential to be highly creative and productive.
McDonald, D.M., Weir, G.R.S.
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A SPATIAL ANALYSIS OF THE ECONOMIC AND ECOLOGICAL EFFICACY OF LAND RETIREMENT [PDF]
Most land management policies, such as land retirement, have multiple objectives. This study uses a cellular automata simulation model to explore how various spatial characteristics of land parcels on a hypothetical landscape contribute to the efficacy ...
Homans, Frances R. +1 more
core +1 more source