Results 151 to 160 of about 1,232,214 (293)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Multiple-choice question – Community medicine and pharmacology

Journal of Integrative Medicine and Research, 2023
Geeta Chand Acharya, Chaitali Pattanayak, Vartika Srivastava   +2 more
doaj   +1 more source

Generating multiple-choice questions using reverse engineering techniques. [PDF]

Med Educ Online
Shin S, Choi J, Hong E, Lee M, Lee M.
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Choice, deferral and consistency

, 2015
Gerasimou and Costa-Gomes gratefully acknowledge financial support from the British Academy (Grant SG122338)In this paper we study decision making in situations where the individual's preferences are not assumed to be complete.
Costa-Gomes, Miguel, Cueva, Carlos, Gerasimou, Georgios   +2 more
core  

Plausible and Proper Multiple-Choice Items for Diagnostic Classification. [PDF]

Psychometrika
Chiu CY, Koehn HF, Wang Y.
europepmc   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Structure and validity of incorrect answers and errors of omission in intelligence testing with multiple choice format

, 2016
As in most time-limited multiple-choice tests, raw scores on intelligence tests are determined by incorrect answers and errors of omission. At the same time, it is known that in cognitive tasks of a medium level of complexity and with no time limit both ...
Rammsayer, Thomas, Troche, Stefan, Borter, Natalie   +2 more
core  

The pitfalls of multiple-choice questions in generative AI and medical education. [PDF]

Sci Rep
Singh S, Alyakin A, Alber DA, Stryker J, Tong APS, Sangwon K, Goff N, De La Paz M, Hernandez-Rovira M, Park KY, Leuthardt EC, Oermann EK.   +11 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source