ABSTRACT Although circulating nucleated red blood cells (cNRBCs) have previously been detected in patients with sickle cell disease (SCD), their prevalence and clinical significance during steady‐state disease have not been established. We retrospectively analyzed 270 adults with an SS or Sβ0‐thalassemia genotype.
Ugo Boccadifuoco +7 more
wiley +1 more source
Constructing a T-Test for Value Function Comparison of Individualized Treatment Regimes in the Presence of Multiple Imputation for Missing Data. [PDF]
Lu M +8 more
europepmc +1 more source
ABSTRACT Nodal T‐follicular helper cell lymphoma (nTFHL), most commonly of angioimmunoblastic type, exhibits heterogeneous clinical outcomes that are not fully explained by current clinical and biological variables. While genetic alterations have been extensively investigated, its proteomic landscape remains largely unexplored.
David Beauvais +9 more
wiley +1 more source
Comparing Multiple Imputation Methods to Address Missing Patient Demographics in Immunization Information Systems: Retrospective Cohort Study. [PDF]
Brown S +5 more
europepmc +1 more source
ABSTRACT Few datasets simultaneously capture occupational exposures and health outcomes in a general working population. To understand associations between occupational exposures and health, researchers often combine existing datasets. As occupation codes are available in many datasets, combining these datasets seems a straight‐forward option. However,
Franziska J. Kößler +3 more
wiley +1 more source
Bias and Efficiency Comparison between Multiple Imputation and Available-Case Analysis for Missing Data in Longitudinal Models. [PDF]
Zhang P, Xie SX.
europepmc +1 more source
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins +9 more
wiley +1 more source
Estimating treatment effect in randomised controlled trials with continuous outcomes subject to non-compliance: a logistic regression-based multiple imputation approach. [PDF]
Du R, Li J, Zhu J, Chan M, Tai BC.
europepmc +1 more source
Trace Elements Genetics: A Potential Role in Treatment‐Resistant Major Psychoses and Related Traits?
ABSTRACT Trace elements are pivotal to key biological processes, with possible effects on psychopathology. We investigated the hypothesis of shared genetic factors between trace elements levels, treatment resistance and related traits. We used genome‐wide summary statistics for trace elements blood concentration, treatment‐resistant depression (TRD ...
Chiara Fabbri +6 more
wiley +1 more source
Comprehensive implementations of multiple imputation using retrieved dropouts for continuous endpoints. [PDF]
Wang S, Schwartz PF, Mancuso JP.
europepmc +1 more source

