Results 61 to 70 of about 435,330 (261)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

SYNTHESIS ALGORITHM OF GEOMETRICAL STRUCTURE OF MIMO RADAR ANTENNA ARRAY

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
In the given work the algorithm of calculation of co-ordinates of elements of MIMO radar antenna is presented. Initial data for algorithm are the number of transmitting, receiving elements, and also demanded number of channels of receiving.
S. A. Gorshkov, P. I. Orgish
doaj  

All-in-one silicon photonic polarization processor

Nanophotonics, 2019
With the great developments in optical communication technology and large-scale optical integration technology, it is imperative to realize the traditional functions of polarization processing on an integration platform. Most of the existing polarization
Zhou Hailong, Zhao Yuhe, Wei Yanxian, Li Feng, Dong Jianji, Zhang Xinliang   +5 more
doaj   +1 more source

Ground-based deformation measurement radar configured with multiple-input multiple-output antennas

The Journal of Engineering, 2019
The application of ground-based radar to monitor the terrain displacement has attracted more and more attentions recently. Most of the existing ground-based radars utilise a linear horizontal rail where the antennas move to generate the image of the test
Haofei Wang, Jiandong Li, Erke Mao, Jian Yang   +3 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

A Dual-Band Multiple Input Multiple Output Frequency Agile Antenna for GPSL1/Wi-Fi/WLAN2400/LTE Applications

International Journal of Antennas and Propagation, 2016
A novel dual-band, single element multiple input multiple output (MIMO) dielectric resonator antenna (DRA) with a modest frequency tuning ability is presented in this communication. The proposed antenna operates at GPS L1/Bluetooth/Wi-Fi/LTE2500/WLAN2400
Sajid Aqeel, M. H. Jamaluddin, Aftab Ahmad Khan, Rizwan Khan, M. R. Kamarudin, Jalil-ur-Rehman Kazim, Owais Owais   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Highly Isolated Multiple-Input Multiple-Output Antenna System for Ingestible Implants

IEEE Journal of Microwaves
In this paper, a dual-antenna multiple-input multiple-output (MIMO) system is designed for deep-tissue indigestible capsules. The system operates at 915 MHz and 2450 MHz frequency bands, covering the desired ISM band.
Amjad Iqbal, Abdul Basir, Muath Al-Hasan, Ismail Ben Mabrouk, Tayeb A. Denidni   +4 more
doaj   +1 more source