Results 61 to 70 of about 453,959 (303)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Modeling of wide-band MIMO radio channels based on NLoS indoor measurements [PDF]

, 2004
In this paper, we first verify a previously proposed Kronecker-structure-based narrow-band model for nonline-of-sight (NLoS) indoor multiple-input-multiple-output (MIMO) radio channels based on 5.2-GHz indoor MIMO channel measurements.
OTTERSTEN, Björn, Bengtsson, Mats,, Peter Karlsson, Yu, K, Bengtsson, B, Karlsson, P, Kai Yu, Beach, Mark, Karlsson, Peter,, Darren Mcnamara, Björn Ottersten, McNamara, Darren,, Mark Beach, Mats Bengtsson, Ottersten, Björn,, Yu, Kai, Karlsson, Peter, McNamara, DP, Yu, Kai,, Beach, Marc,, Ottersten, P, McNamara, Darren, Student Member, Beach, MA, Bengtsson, Mats   +24 more
core   +1 more source

A Janus compatible software-defined underwater acoustic multiple-input multiple-output modem

International Journal of Distributed Sensor Networks, 2021
This article describes the implementation of a multiple-input multiple-output acoustic communication link in shallow water conditions to enable a software-defined acoustic modem with a maximum transmission rate of 20 kbps in a 5-kHz bandwidth.
Surinder Singh, Mark Crispo, Jean-François Bousquet, Shadi Aljendi   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Adaptive relaying protocol multiple-input multiple-output orthogonal frequency division multiplexing systems [PDF]

, 2014
In wireless broadband communications, orthogonal frequency division multiplexing (OFDM) has been adopted as a promising technique to mitigate multi-path fading and provide high spectral efficiency.
Sileh, Ibrahim Khalil
core  

Multiple-input multiple-output vs. Single-input single-output neural network forecasting [PDF]

, 2015
This study attempts to improve the forecasting accuracy of tourism demand by using the existing common trends in tourist arrivals form all visitor markets to a specific destination in a multiple-input multiple-output (MIMO) structure. While most tourism forecasting research focuses on univariate methods, we compare the performance of three different ...
Claveria González, Oscar, Monte Moreno, Enrique, Torra Porras, Salvador   +2 more
openaire   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

An Enhanced Precoder for Multi User Multiple-Input Multiple-Output Downlink Systems

Applied Sciences, 2020
Recently, as the demand for data rate of users has increased, wireless communication systems have aimed to offer high throughput. For this reason, various techniques which guarantee high performance have been invented, such as massive multiple-input ...
Woon-Sang Lee, Jae-Hyun Ro, Young-Hwan You, Duckdong Hwang, Hyoung-Kyu Song   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source