Results 61 to 70 of about 15,331 (264)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
On multi-propagator angular integrals
Journal of High Energy PhysicsWe study multi-propagator angular integrals, a class of phase-space integrals relevant to processes with multiple observed final states and a test-bed for transferring loop-integral technology to phase-space integrals without reversed unitarity.
Juliane Haug +2 more
doaj +1 more source
Master integrals of a planar double-box family for top-quark pair production
Physics Letters B, 2019 We calculate analytically the master integrals of a planar double-box family for top-quark pair production using the method of differential equations. With a proper choice of the bases, the differential equations can be transformed to the d-log form. The
Long-Bin Chen, Jian Wang
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Journal of High Energy PhysicsAngular integrals arise in a wide range of perturbative quantum field theory calculations. In this work we investigate angular integrals with three denominators in d = 4 – 2ε dimensions.
Juliane Haug, Fabian Wunder
doaj +1 more source
Elliptic polylogarithms and Feynman parameter integrals
Journal of High Energy Physics, 2019 In this paper we study the calculation of multiloop Feynman integrals that cannot be expressed in terms of multiple polylogarithms. We show in detail how certain types of two- and three-point functions at two loops, which appear in the calculation of ...
Johannes Broedel +4 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source