scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta +3 more
wiley +1 more source
Random subspace-based ensemble classifier for high-dimensional data Using SPARK. [PDF]
Bhimineni VC, Senapati R.
europepmc +1 more source
A machine learning framework simultaneously predicts four critical properties of monomers for emulsion polymerization: propagation rate constant, reactivity ratios, glass transition temperature, and water solubility. These tools can be used to systematically identify viable bio‐based monomer pairs as replacements for conventional formulations, with ...
Kiarash Farajzadehahary +1 more
wiley +1 more source
Integrating Distance Correlation and Adaptive Weighting with RBF Kernel Transformations: A Novel Feature Selection Framework with Application to ECG Arrhythmia Detection. [PDF]
Fira M, Fira L.
europepmc +1 more source
AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source
FLF-RCNN: A Fine-Tuned Lightweight Faster RCNN for Precise and Efficient Industrial Quality Inspection. [PDF]
An N, Yang Z, Wan L, Li J, Wang Y.
europepmc +1 more source
Uncertainty‐Guided Selective Adaptation Enables Cross‐Platform Predictive Fluorescence Microscopy
Deep learning models often fail when transferred to new microscopes. A novel framework overcomes this by selectively adapting the early layers governing low‐level image statistics, while freezing deep layers that encode morphology. This uncertainty‐guided approach enables robust, label‐free virtual staining across diverse systems, democratizing ...
Kai‐Wen K. Yang +9 more
wiley +1 more source
Kernel mean matching enhances risk estimation under spatial distribution shifts. [PDF]
Serov E, Koldasbayeva D, Zaytsev A.
europepmc +1 more source
Materials informatics and autonomous experimentation are transforming the discovery of organic molecular crystals. This review presents an integrated molecule–crystal–function–optimization workflow combining machine learning, crystal structure prediction, and Bayesian optimization with robotic platforms.
Takuya Taniguchi +2 more
wiley +1 more source
Letter to the Editor: Advancing deep learning-based segmentation for multiple lung cancer lesions in real-world multicenter CT scans. [PDF]
Huang X, Gu X.
europepmc +1 more source

