Results 41 to 50 of about 2,203,514 (272)

Metabolism of ticagrelor in patients with acute coronary syndromes. [PDF]

open access: yes, 2018
© The Author(s) 2018Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation to exert its ...
B Ibanez   +41 more
core   +2 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

Lasso Estimation of an Interval-Valued Multiple Regression Model

open access: yes, 2015
A multiple interval-valued linear regression model considering all the cross-relationships between the mids and spreads of the intervals has been introduced recently.
A. Blanco-Fernández   +6 more
core   +1 more source

A Comparative Study of Cerebral Oxygenation During Exercise in Hemodialysis and Peritoneal Dialysis Patients

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou   +10 more
wiley   +1 more source

PENGARUH FAKTOR-FAKTOR PRODUKSI TERHADAP PENDAPATAN PETANI GAMBIR DI KECAMATAN PANGKALAN KOTO BARU KABUPATEN LIMA KOTA

open access: yesZiraa'ah: Majalah Ilmiah Pertanian, 2022
The aim of this study is to examine the effects of land area, labor, production costs, production quantities, and prices simultaneously and partially on the income of gambier farmers in Pangkalan Koto Baru District.
Ana Tasya Rahima   +2 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Varying-coefficient functional linear regression [PDF]

open access: yes, 2010
Functional linear regression analysis aims to model regression relations which include a functional predictor. The analog of the regression parameter vector or matrix in conventional multivariate or multiple-response linear regression models is a ...
Fan, Jianqing   +2 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Using the Hybrid MLR-GA Approach for Air Pollution Forecasting [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2019
Air Quality Modeling gained great importance in atmospheric pollution because of its negative effects on the environment and human health. In our study, the relationship between (Particulate Matter PM10) and other nine variables over three years is ...
Fanar Abdul Razaq Mohammed   +1 more
doaj   +1 more source

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