Results 71 to 80 of about 2,240,564 (272)
In order to have an optimum development of hydrocarbon reservoirs, it is necessary to use a numerical simulation of reservoirs in which a large amount of geological and reservoir parameters are needed; therefore, an adequate record of information is ...
Fidel Vladimir Chuchuca Aguilar +4 more
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Semiparametrically efficient estimation of the average linear regression function
Let Y be an outcome of interest, X a vector of treatment measures, and W a vector of pre-treatment control variables. Here X may include (combinations of) continuous, discrete, and/or non-mutually exclusive "treatments". Consider the linear regression of
Graham, Bryan S. +1 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Local bilinear multiple-output quantile/depth regression
A new quantile regression concept, based on a directional version of Koenker and Bassett's traditional single-output one, has been introduced in [Ann. Statist. (2010) 38 635-669] for multiple-output location/linear regression problems.
Hallin, Marc +3 more
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Chemometric modeling of bioconcentration factor of 6-chloro-1,3,5-triazine derivatives based on MLR-QSPR approach [PDF]
Pesticides have an important role in agriculture since they can prevent large crop losses which is crucial in order to keep pace with population growth that is estimated to be 9.7 billion people by the year 2050.
Karadžić-Banjac Milica +3 more
doaj +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A Comparing Robust Wilks’ statistics in Multivariate Multiple Linear Regression
In multivariate linear regression, the classical Wilks’ statistic is the most used method to test hypotheses, which is extremely responsive to the effect of outliers.
Thamer, Abdullah A. Ameen
doaj +1 more source

