Results 61 to 70 of about 7,261,189 (227)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Perception, Distance Estimation, and Tracking Integration From BEV Representations

IEEE Access
Strong perception, precise distance estimate, and dependable object tracking are necessary for autonomous vehicle systems to function. To improve autonomous driving capabilities, we describe a unique deep learning-based fusion architecture in this paper ...
Saidrasul Usmankhujaev, Shokhrukh Baydadaev, Jang Woo Kwon   +2 more
doaj   +1 more source

Deep learning for multiple object tracking: a survey

IET Computer Vision, 2019
Deep learning has been proved effective in multiple object tracking, which confronts the difficulties of frequent occlusions, confusing appearance, in‐and‐out objects, and lack of enough labelled data.
Yingkun Xu, Xiaolong Zhou, Shengyong Chen, Fenfen Li   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

EnhanceCenter for improving point based tracking and rich feature representation

Scientific Reports
In this study, we propose EnhanceCenter, a multiple-object tracking model that demonstrates enhanced tracking efficiency and stability while reducing dependencies on computationally intensive detectors.
Hyun-Sung Yang, Sung-Wook Park, Se-Hoon Jung, Chun-Bo Sim   +3 more
doaj   +1 more source

YOLOv8MS: Algorithm for Solving Difficulties in Multiple Object Tracking of Simulated Corn Combining Feature Fusion Network and Attention Mechanism

Agriculture
The automatic cultivation of corn has become a significant research focus, with precision equipment operation being a key aspect of smart agriculture’s advancement.
Yuliang Gao, Zhen Li, Bin Li, Lifeng Zhang   +3 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Self-correcting Bayesian target tracking [PDF]

, 2015
The copyright of this thesis rests with the author and no quotation from it or information derived from it may be published without the prior written consent of the authorAbstract Visual tracking, a building block for many applications, has challenges ...
Biresaw, Tewodros Atanaw
core   +4 more sources

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

AFMtrack: Attention-Based Feature Matching for Multiple Object Tracking

IEEE Access
Real-time multiple object tracking plays a pivotal role in autonomous driving applications, particularly in real-world applications. Current methods in various domains often face an inherent trade-off between accuracy and speed.
Duy Cuong Bui, Hiep Anh Hoang, Myungsik Yoo   +2 more
doaj   +1 more source